Contact Dr Celia Lourenco
Areas of expertise
- Biomedical Engineering
- Biosensors & Diagnostics
- Environment and Health
Dr Célia Lourenço obtained her PhD in 2017 in Analytical Chemistry at The Open University (UK). She was awarded with a Marie Curie Fellowship (FP7-PEOPLE-2011-ITN) through which she obtained training and developed a broad range of skills in different areas of research. Her PhD project involved mass spectrometry-based metabolomics in health monitoring, through the use of the analysis of volatile organic compounds allowing the screening and monitoring of different diseases and conditions, non-invasively and painlessly.
Her previous work experience in mass spectrometry was acquired throughtout her research work at Instituto Superior Técnico, Universidade Técnica de Lisboa (Portugal) and at Commissariat à l'énergie atomique et aux énergies alternatives, CEA Marcoule (France). She developed thermochemical gas-phase mass spectrometry studies with radioactive elements and transition metal oxides 4d and 5d.
Before graduating in 2010 from the Instituto Superior de Engenharia de Lisboa (Portugal) with a MSc in Chemical Engineering, she joined Hovione FarmaCiencia SA in Portugal for a 6 months placement as a trainee in R&D Analytical Chemistry Department, where she has gathered competences in mass spectrometry and chromatography.
Celia joined Cranfield in 2017 and studied the effects of the introduction of new composite materials in the aircraft structure and cabin. Analysis of volatile organic compounds (VOCs) potentially generated during flight due to thermal degradation of composite materials, and potentially hazardous for human health.
She is currently involved in delivering an EPSRC research project entitled "Point of care diagnosis of gastrointestinal disease using laser spectroscopy".
Celia is involved in teaching activities and supervision of MSc students.
Research activities carried out through the use of highly sensitive analytical techniques such as Mass spectrometry coupled to Gas Chromatography (GC-MS), Selected Ion Flow Tube Mass Spectrometry (SIFT-MS) or Proton Transfer Reaction Mass Spectrometry (PTR-MS) for the analysis of Volatile Organic compounds (VOCs) present in different sample matrices. Research interests include the study of chemical processes involving metabolites (Metabolomics); Biomarker discovery; Gas phase ion chemistry; Environment and Health; Chemical Exposure.
Articles In Journals
- Lourenço C, Bergin S, Hodgkinson J, Francis D, Staines SE, Saffell JR, Walton C & Tatam RP (2020) Instrumentation for quantitative analysis of volatile compounds emission at elevated temperatures. Part 1: Design and implementation, Scientific Reports, 10 (1) Article No. 8700.
- Lourenço C, Francis D, Fowler DP, Staines SE, Hodgkinson J, Walton C, Bergin S & Tatam RP (2020) Instrumentation for quantitative analysis of volatile compounds emission at elevated temperatures. Part 2: Analysis of carbon fibre reinforced epoxy composite, Scientific Reports, 10 (1) Article No. 8702.
- Lourenço C, Kelly D, Cantillon J, Cauchi M, Yon MA, Bentley L, Cox RD & Turner C (2019) Monitoring type 2 diabetes from volatile faecal metabolome in Cushing’s syndrome and single Afmid mouse models via a longitudinal study, Scientific Reports, 9 Article No. 18779.
- Monteiro B, Bandeira NAG, Lourenço C, Lucena AF, Carretas JM, Gibson JK & Marçalo J (2019) Chemical evidence of the stability of praseodymium(v) in gas-phase oxide nitrate complexes, Chemical Communications, 55 (94) 14139-14142.
- Lourenco C, Gonzalez-Mendez R, Reich F, Mason N & Turner C (2017) A potential method for comparing instrumental analysis of volatile organic compounds using standards calibrated for the gas phase, International Journal of Mass Spectrometry, 419 (August) 1-10.
- Batty CA, Cauchi M, Lourenco C, Hunter JO & Turner C (2015) Use of the analysis of the volatile faecal metabolome in screening for colorectal cancer, PLoS ONE, 10 (6).
- Lucena AF, Lourenco C, Michelini MC, Rutkowski PX, Carretas JM, Zorz N, Berthon L, Dias A, Oliveira MC, Gibson JK & Marcalo J (2015) Synthesis and hydrolysis of gas-phase lanthanide and actinide oxide nitrate complexes: a correspondence to trivalent metal ion redox potentials and ionization energies, Physical Chemistry Chemical Physics, 17 (15) 9942-9950.
- Lourenço C & Turner C (2014) Breath analysis in disease diagnosis: methodological considerations and applications, Metabolites, 4 (2) 465-498.
- Lourenco C, Michelini MD, Marcalo J, Gibson JK & Oliveira MC (2012) Gas-phase reaction studies of dipositive hafnium and hafnium oxide ions: generation of the peroxide HfO22+, Journal of Physical Chemistry A, 116 (51) 12399-12405.
- Santos M, Michelini MD, Lourenco C, Marcalo J, Gibson JK & Oliveira MC (2012) Gas-phase oxidation reactions of Ta2+: synthesis and properties of TaO2+ and TaO22+, Journal of Physical Chemistry A, 116 (14) 3534-3540.