Contact Professor Peter Zioupos
Areas of expertise
- Ageing & Chronic Disease
- Biomedical Engineering
- Human Factors for Defence
Background
Education
DSc: Bioengineering, Faculty of Engineering, Strathclyde University (2007); 'Composite aspects of basic bone biomechanics: structure/function relationships and applications'.
PhD: Bioengineering, Faculty of Engineering, Strathclyde University (1989); Tissue mechanics of Bioprosthetic heart valves.
BSc: Physics, University of Ioannina Greece (1983)
Other Websites
https://scholar.google.co.uk/citations?hl=en&user=gmGZ-8cAAAAJ
https://orcid.org/0000-0002-0123-2706
https://www.linkedin.com/in/dr-peter-zioupos-aa1126a6/
https://www.researchgate.net/profile/peter-Zioupos
https://exaly.com/author/2453455/peter-zioupos
Interests
Biomedical Engineering; Biomechanics of Materials; Ageing & Chronic Disease; Human Factors for Defence; Forensic Biomechanics;
Profile
Peter Zioupos is a Professor in Biomedical Engineering in School of Engineering in University of Hull. He has held previous appointments in the universities of Cranfield, York and Strathclyde.
He has an interest in Musculoskeletal science and research and their link to Orthopaedic Biomechanics, Bone physiology, Bone ageing, Anatomy and Forensics.
He is a Visiting Professor of the Institute of Future Transport & Cities of Coventry University (Nov 2020) advising on automotive related trauma and applications, a Visiting Fellow in CFI at Cranfield University and also a Fellow of the IPEM (Institute of Physics and Engineering in Medicine). In 2008, he was awarded the Degree of Doctor of Science by the Senate of Strathclyde University following the recommendation by the Higher Doctorates Committee for his work on 'Composite aspects of basic bone biomechanics: structure/function relationships and applications'. Over the past 20 years he has published over 100 peer review articles in this specialised topic, gathering over 6100 citations. 13 papers, in particular, are now 'classics' in the field of basic bone biomechanics with more than 100 citations each.
He is in the Editorial advisory board of the Journal of Biomechanics (ELSEVIER) and the Editorial boards of the Journal of Mechanical Behaviour of Biomedical Materials (ELSEVIER), Journal of Bionic Engineering (SPRINGER), Frontiers in Bioengineering and Biotechnology (section Biomechanics) and LIFE (MDPI) and LIFE (MDPI). He was the guest editor for a Special issue of the 'Journal of Mechanical Behavior of Biomedical Materials' on 'Forensic Biomechanics' (May 2014) which presents a good choice of papers across a range of applications in the field of Medicolegal Biomechanics.
Publishing opportunities
Peter Zioupos is presently compiling a special issue in LIFE called: "Hard and Soft Tissue Biomechanics 'In Translation'" to which papers are now invited for submission https://www.mdpi.com/journal/life/special_issues/Y4Q28H3138. The Special issue topics are: (1) Biomechanics of cells, tissues, and biomaterials; (2) Hard-soft tissue interface; (3) Bioinspired 3D printed and electro-spun materials; (4) Imaging-based mechanics of tissues and biomaterials; (5) Deep learning and computational modelling; (6) Other techniques with the potential to complement, inform, and expand knowledge of hard and soft tissues.
Current activities
His most recent work was in detecting the arrival of 'maturity' in the human skeleton by biomechanical and physicochemical methods (BONE in 2022) and on the influence of varying strain rate on the properties of bone (BONE in 2020). In the latter a paradigm shifting paper he has shown that the fragility of ageing bone in particular is a result of a ductile-to-brittle-transition (DBT) which shifts to lower strain rates for older individuals. The cause of this effect is biophysical in its nature and shows that the so called 'bone properties' can only be understood in the context of its history and its environment both mechanical and ambient. The content and context of this new way of looking at bone fracture as a 'dynamic' material which experiences failure in a 'stochastic' manner were presented in a special issue of the journal BONE https://www.sciencedirect.com/journal/bone/special-issue/10VZ6CMZR77 and in a WEBINAR (19 Nov 2020) given in memory of the late John D Currey for JMBBM (J Mechanical Properties of Biomedical Materials) YouTube: https://youtu.be/BuYBImaAc28
PZ is also active in forensics and offers consultancy in legal cases regarding lethal or otherwise trauma, which involves primarily bone injuries. He has developed a patent for the Forensic determination of age at time of death by analytical laboratory examination of bone matrix. He offers consultancy to industry via nanoindentation studies on various health care products, on anodising layers, design of test chambers and testing standards. He has appeared in TV documentaries: one for Discovery Channel on "free fall" accidents, and in National Geographic on the circumstances surrounding the unexpected "death of King Tutankhamen". A more recent presentation was in BBC2 the 'AUTUMNWATCH' programme (31 October 2019). Peter was interviewed on the comparative properties of bone and antler material. A structure/function link was made on screen between the gross anatomy and material properties of these two very different kinds of bone and their function/performance in life.
Publications
Articles In Journals
- Cai Y, Pascoletti G, Zioupos P, Budair B, Zanetti EM, .... (2024). Parametrization of the Calcaneus and Medial Cuneiform to Aid Potential Advancements in Flatfoot Surgery. Life, 14(3)
- Leslie G, Winwood K, Sanderson A, Zioupos P & Allen T. (2023). Feasibility of additively manufacturing synthetic bone for sports personal protective equipment applications. Annals of 3D Printed Medicine, 12
- Bonicelli A, Tay T, Cobb JP, Boughton OR, Hansen U, .... (2023). Association between nanoscale strains and tissue level nanoindentation properties in age-related hip-fractures. Journal of the Mechanical Behavior of Biomedical Materials, 138(February)
- Walden SJ, Rowe W, Mulville J, Evans SL & Zioupos P. (2023). Quantifying microcracks on fractured bone surfaces – Potential use in forensic anthropology. Journal of the Mechanical Behavior of Biomedical Materials, 142(June)
- Maier AK, Manzella A, Bonicelli A, Arnold EL, Márquez-Grant N, .... (2023). Wet Bone Characteristics Persist in Buried Bone after 10 Weeks: Implications for Forensic Anthropology. Forensic Sciences, 3(3)
- Bishop N, Zioupos P & Offiah AC. (2023). A focus on fractures: Understanding and addressing fracture risk in rare bone disorders. JBMR PLUS, 7
- Bonicelli A, Kranioti EF, Xhemali B, Arnold E & Zioupos P. (2022). Assessing bone maturity: Compositional and mechanical properties of rib cortical bone at different ages. Bone, 155(February)
- GJ A, RB C, JR H & P Z. (2022). Microarchitecture and morphology of bone tissue over a wide range of BV/TV assessed by micro-computed tomography and three different threshold backgrounds. Medical Engineering & Physics, 106(August)
- Berli M, Franco F, Di Paolo J, Zioupos P & Borau C. (2022). The interplay between BMU activity linked to mechanical stress, specific surface and inhibitory theory dictate bone mass distribution: Predictions from a 3D computational model. Computers in Biology and Medicine, 148(September)
- Bastien C. (2021). A Generic Brain Trauma Computer Framework to Assess Brain Injury Severity and Bridging Vein Rupture in Traumatic Falls. Journal of Head Neck & Spine Surgery, 4(4)
- Bonicelli A, Zioupos P, Arnold E, Rogers KD, Xhemali B, .... (2021). Age related changes of rib cortical bone matrix and the application to forensic age-at-death estimation. Scientific Reports, 11(1)
- Franceskides C, Gibson M & Zioupos P. (2020). Evaluation of bone excision effects on a human skull model—II: Finite element analysis. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 234(4)
- Zioupos P, Kirchner HOK & Peterlik H. (2020). Ageing bone fractures: The case of a ductile to brittle transition that shifts with age. Bone, 131
- Franceskides C, Leger T, Horsfall I, Tozzi G, Gibson M, .... (2020). Evaluation of bone excision effects on a human skull model – I: Mechanical testing and digital image correlation. Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 234(4)
- McGivern H, Greenwood C, Márquez-Grant N, Kranioti EF, Xhemali B, .... (2020). Age-Related Trends in the Trabecular Micro-Architecture of the Medial Clavicle: Is It of Use in Forensic Science?. Frontiers in Bioengineering and Biotechnology, 7
- Franceskides C, Arnold E, Horsfall I, Tozzi G, Gibson MC, .... (2020). Spinal Motion Segments — I: Concept for a Subject-specific Analogue Model. Journal of Bionic Engineering, 17(4)
- Franceskides C, Arnold E, Horsfall I, Tozzi G, Gibson MC, .... (2020). Spinal Motion Segments — II: Tuning and Optimisation for Biofidelic Performance. Journal of Bionic Engineering, 17(4)
- Currey JD, Brear K & Zioupos P. (2019). Strain rate dependence of work of fracture tests on bone and similar tissues: Reflections on testing methods and mineral content effects. Bone, 128
- Vidal B, Cascão R, Finnilä MAJ, Lopes IP, da Glória VG, .... (2019). Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model. Rheumatology, 58(2)
- Greenwood C, Clement J, Dicken A, Evans P, Lyburn I, .... (2018). Age-Related Changes in Femoral Head Trabecular Microarchitecture. Aging and disease, 9(6)
- Mooring L, Thompson S, Hall SA, Pani S, Zioupos P, .... (2018). ‘Phoenix polymers’: fire induced nanohardness in fibril-forming aromatic cyanate esters. RSC Advances, 8(63)
- Vidal B, Cascão R, Finnilä MAJ, Lopes IP, da Glória VG, .... (2018). Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model. Rheumatology, 57(8)
- Vidal B, Cascão R, Finnilä MAJ, Lopes IP, Saarakkala S, .... (2018). Early arthritis induces disturbances at bone nanostructural level reflected in decreased tissue hardness in an animal model of arthritis. PLOS ONE, 13(1)
- Bradley M, Martin I, Roelofs A, Khosla S, Mahajan S, .... (2018). Bone Research Society Abstracts. JBMR Plus, 2(S1)
- Adams GJ, Cook RB, Hutchinson JR & Zioupos P. (2018). Bone Apparent and Material Densities Examined by Cone Beam Computed Tomography and the Archimedes Technique: Comparison of the Two Methods and Their Results. Frontiers in Mechanical Engineering, 3
- Macoveciuc I, Márquez-Grant N, Horsfall I & Zioupos P. (2017). Sharp and blunt force trauma concealment by thermal alteration in homicides: An in-vitro experiment for methodology and protocol development in forensic anthropological analysis of burnt bones. Forensic Science International, 275
- Bonicelli A, Xhemali B, Kranioti EF & Zioupos P. (2017). Rib biomechanical properties exhibit diagnostic potential for accurate ageing in forensic investigations. PLOS ONE, 12(5)
- Berli M, Borau C, Decco O, Adams G, Cook RB, .... (2017). Localized tissue mineralization regulated by bone remodelling: A computational approach. PLOS ONE, 12(3)
- Bonicelli A, Zioupos P, Papadomanolakis A & Kranioti EF. (2017). Case study: Age estimation using structural, chemical, and biomechanical data of a modern rib retrieved from the seashore. La Revue de Médecine Légale, 8(4)
- Mohamad NS, Sinadinos A, Górecki DC, Zioupos P & Tong J. (2016). Impact of P2RX7 ablation on the morphological, mechanical and tissue properties of bones in a murine model of duchenne muscular dystrophy. Journal of Biomechanics, 49(14)
- Greenwood C, Clement J, Dicken A, Evans JPO, Lyburn I, .... (2016). Towards new material biomarkers for fracture risk. Bone, 93
- Dicken AJ, Evans JPO, Rogers KD, Stone N, Greenwood C, .... (2016). Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter. Scientific Reports, 6(1)
- Dall'Ara E, Grabowski P, Zioupos P & Viceconti M. (2015). Estimation of local anisotropy of plexiform bone: Comparison between depth sensing micro-indentation and Reference Point Indentation. Journal of Biomechanics, 48(15)
- Crawford SR, Burden AM, Yates JM, Zioupos P & Winwood K. (2015). Can Masticatory Electromyography be Normalised to Submaximal Bite Force?. Journal of Oral Rehabilitation, 42(5)
- Dicken AJ, Evans JPO, Rogers KD, Stone N, Greenwood C, .... (2015). X-ray diffraction from bone employing annular and semi-annular beams. Physics in Medicine and Biology, 60(15)
- Dicken AJ, Evans JPO, Rogers KD, Greenwood C, Godber SX, .... (2015). Energy-dispersive X-ray diffraction using an annular beam. Optics Express, 23(10)
- Greenwood C, Clement JG, Dicken AJ, Evans JPO, Lyburn ID, .... (2015). The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue. Bone Reports, 3
- Asgharpour Z, Zioupos P, Graw M & Peldschus S. (2014). Development of a strain rate dependent material model of human cortical bone for computer-aided reconstruction of injury mechanisms. Forensic Science International, 236
- Zioupos P. (2014). Forensic biomechanics. Journal of the Mechanical Behavior of Biomedical Materials, 33(1)
- Zioupos P, Williams A, Christodoulou G & Giles R. (2014). Determining ‘age at death’ for forensic purposes using human bone by a laboratory-based biomechanical analytical method. Journal of the Mechanical Behavior of Biomedical Materials, 33(1)
- Akbarzadeh J, Puchegger S, Stojanovic A, Kirchner HOK, Binder WH, .... (2014). Timescales of self-healing in human bone tissue and polymeric ionic liquids. Bioinspired, Biomimetic and Nanobiomaterials, 3(3)
- Herlin M, Finnilä MAJ, Zioupos P, Aula A, Risteli J, .... (2013). New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties. Toxicology and Applied Pharmacology, 273(1)
- Ural A, Zioupos P, Buchanan D & Vashishth D. (2012). Evaluation of the influence of strain rate on Colles' fracture load. Journal of Biomechanics, 45(10)
- Ertas AH, Winwood K, Zioupos P & Cotton JR. (2012). Simulation of creep in non-homogenous samples of human cortical bone. Computer Methods in Biomechanics and Biomedical Engineering, 15(10)
- Hudson RJ, Zioupos P & Gill PP. (2012). Investigating the Mechanical Properties of RDX Crystals Using Nano‐Indentation. Propellants, Explosives, Pyrotechnics, 37(2)
- Hicks K-M, Winwood K, Minnock E & Zioupos P. (2012). COULD THE ORAL CONTRACEPTIVE PILL (OCP) HAVE A POSITIVE EFFECT ON THE REDUCTION OF FRACTURE RISK IN LATER LIFE?. Journal of Biomechanics, 45
- Minnock E, Fallowfield JL, Dziubak A, Leiper R & Zioupos P. (2012). STRESS FRACTURES IN FORCES RECRUITS: A CASE STUDY IN THE UK. Journal of Biomechanics, 45
- Ural A, Zioupos P, Buchanan D & Vashishth D. (2011). The effect of strain rate on fracture toughness of human cortical bone: A finite element study. Journal of the Mechanical Behavior of Biomedical Materials, 4(7)
- Cook RB, Curwen C, Tasker T & Zioupos P. (2010). Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements. Medical Engineering & Physics, 32(9)
- Finnilä MAJ, Zioupos P, Herlin M, Miettinen HM, Simanainen U, .... (2010). Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties. Journal of Biomechanics, 43(6)
- Cook RB & Zioupos P. (2010). Corrigendum to “The fracture toughness of cancellous bone”. Journal of Biomechanics, 43(7)
- Zioupos P, Currey JD & Casinos A. (2010). Osteopetrosis, pachyostosis and the structural skeletal adaptations in Dugong Dugon. Bone, 47
- Cook RB & Zioupos P. (2009). The fracture toughness of cancellous bone. Journal of Biomechanics, 42(13)
- Zioupos P, Cook RB & Hutchinson JR. (2009). More thoughts on the relationship between apparent and material densities in bone. Journal of Biomechanics, 42(6)
- Zioupos P, Hansen U & Currey JD. (2008). Microcracking damage and the fracture process in relation to strain rate in human cortical bone tensile failure. Journal of Biomechanics, 41(14)
- Gupta HS & Zioupos P. (2008). Fracture of bone tissue: The ‘hows’ and the ‘whys’. Medical Engineering & Physics, 30(10)
- Zioupos P, Gresle M & Winwood K. (2008). Fatigue strength of human cortical bone: Age, physical, and material heterogeneity effects. Journal of Biomedical Materials Research Part A, 86A(3)
- Minnock E, Cook R, Collins D, Tucker J & Zioupos P. (2008). Using Risk Factors and Quantitative Ultrasound to Identify Postmenopausal Caucasian Women at Risk of Osteoporosis. Journal of Clinical Densitometry, 11(4)
- Hansen U, Zioupos P, Simpson R, Currey JD & Hynd D. (2008). The Effect of Strain Rate on the Mechanical Properties of Human Cortical Bone. Journal of Biomechanical Engineering, 130(1)
- Zioupos P, Cook RB & Hutchinson JR. (2008). Some basic relationships between density values in cancellous and cortical bone. Journal of Biomechanics, 41(9)
- Minnock E, Zioupos P, Cook R, Collins D & Tucker J. (2008). CAN QUESTIONNAIRES AND QUANTITATIVE ULTRASOUND BE USED TO SCREEN FOR OSTEOPOROSIS?. Journal of Biomechanics, 41
- Minnock E, Winwood K & Zioupos P. (2008). USING QUANTITATIVE ULTRASOUND TO PREDICT BONE STRUCTURE. Journal of Biomechanics, 41
- Finnilä M, Zioupos P, Tuukkanen J, Viluksela M & Jämsä T. (2008). EFFECTS OF 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN (TCDD) EXPOSURE ON BONE NANOMECHANICAL PROPERTIES. Journal of Biomechanics, 41
- Zioupos P & Kirchner HOK. (2008). FRAGILITY IN OLD BONES: A CASE FOR A DUCTILE TO BRITTLE TRANSITION SHIFT WITH AGE. Journal of Biomechanics, 41
- Winwood K & Zioupos P. (2008). MICROSTRUCTURAL AND PHYSICAL EFFECTS IN THE FATIGUE BEHAVIOUR OF HUMAN CORTICAL BONE. Journal of Biomechanics, 41
- Blythe A, Tasker T & Zioupos P. (2006). ACL graft constructs: In-vitro fatigue testing highlights the occurrence of irrecoverable lengthening and the need for adequate (pre)conditioning to avert the recurrence of knee instability. Technology and Health Care, 14(4-5)
- Winwood KL, Zioupos P, Currey JD, Cotton JR & Taylor M. (2006). The importance of the elastic and plastic components of strain in tensile and compressive fatigue of human cortical bone in relation to orthopaedic biomechanics. Journal of Musculoskeletal Neuronal Interactions, 6(2)
- Winwood K, Zioupos P, Currey JD, Cotton JR & Taylor M. (2006). Strain patterns during tensile, compressive, and shear fatigue of human cortical bone and implications for bone biomechanics. Journal of Biomedical Materials Research Part A, 79A(2)
- Zioupos P & Rogers KD. (2006). Complementary physical and mechanical techniques to characterise tooth: A bone-like tissue. Journal of Bionic Engineering, 3(1)
- Moniruzzaman M, Zioupos P & Fernando GF. (2006). Investigation of reversible photo-mechanical properties of azobenzene-based polymer films by nanoindentation. Scripta Materialia, 54(2)
- Zioupos P & Rogers KD. (2006). Complementary physical and mechanical techniques to characterise tooth: a bone-like tissue. Journal of Biomechanics, 39
- Cook RB, Zioupos P, Curwen C & Tasker T. (2006). Using peripheral quantitative ultrasound to predict fracture mechanics and compressive properties at the head of the femur. Journal of Biomechanics, 39
- Sedman A, Currey J & Zioupos P. (2006). The fracture process in mineralised tissues visualised by whitening, an indicator of microdamage. Journal of Biomechanics, 39
- Zioupos P, Hansen U & Currey J. (2006). The development of microdamage as a function of strain rate in human cortical bone. Journal of Biomechanics, 39
- Cook RB & Zioupos P. (2006). The fracture toughness of cancellous bone. Journal of Biomechanics, 39
- Cook RB, Collins D, Tucker J & Zioupos P. (2005). Comparison of questionnaire and quantitative ultrasound techniques as screening tools for DXA. Osteoporosis International, 16(12)
- Cook RB, Collins D, Tucker J & Zioupos P. (2005). The ability of peripheral quantitative ultrasound to identify patients with low bone mineral density in the hip or spine. Ultrasound in Medicine & Biology, 31(5)
- Cotton JR, Winwood K, Zioupos P & Taylor M. (2005). Damage Rate is a Predictor of Fatigue Life and Creep Strain Rate in Tensile Fatigue of Human Cortical Bone Samples. Journal of Biomechanical Engineering, 127(2)
- P. ZIOUPOS . (2005). In vivo fatigue microcracks in human bone: Material properties of the surrounding bone matrix. European Journal of Morphology, 42(1-2)
- Currey JD, Brear K & Zioupos P. (2004). Notch sensitivity of mammalian mineralized tissues in impact. Proceedings of the Royal Society of London. Series B: Biological Sciences, 271(1538)
- Coats AM, Zioupos P & Aspden RM. (2003). Material Properties of Subchondral Bone from Patients with Osteoporosis or Osteoarthritis by Microindentation testing and Electron Probe Microanalysis. Calcified Tissue International, 73(1)
- Cotton JR, Zioupos P, Winwood K & Taylor M. (2003). Analysis of creep strain during tensile fatigue of cortical bone. Journal of Biomechanics, 36(7)
- Rho JY, Zioupos P, Currey JD & Pharr GM. (2002). Microstructural elasticity and regional heterogeneity in human femoral bone of various ages examined by nano-indentation. Journal of Biomechanics, 35(2)
- Rho J-Y, Currey JD, Zioupos P & Pharr GM. (2001). The Anisotropic Young’s Modulus of Equine Secondary Osteones and Interstitial Bone Determined by Nanoindentation. Journal of Experimental Biology, 204(10)
- ZIOUPOS P, CURREY JD & CASINOS A. (2001). Tensile Fatigue in Bone: Are Cycles-, or Time to Failure, or Both, Important?. Journal of Theoretical Biology, 210(3)
- Currey JD, Zioupos P, Peter D & Casinos A. (2001). Mechanical properties of nacre and highly mineralized bone. Proceedings of the Royal Society of London. Series B: Biological Sciences, 268(1462)
- Currey JD & Zioupos P. (2001). The effect of porous microstructure on the anisotropy of bone-like tissue:. Journal of Biomechanics, 34(5)
- Zioupos P. (2001). Ageing Human Bone: Factors Affecting its Biomechanical Properties and the Role of Collagen. Journal of Biomaterials Applications, 15(3)
- Zioupos P. (2001). Accumulation of in-vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone.. J Microsc, 201(2)
- Zioupos P, Currey JD & Casinos A. (2000). Exploring the Effects of Hypermineralisation in Bone Tissue by Using an Extreme Biological Example. Connective Tissue Research, 41(3)
- Rho JY, Zioupos P, Currey JD & Pharr GM. (2000). Letter to the editor: Response. Bone, 26(5)
- Rho JY, Zioupos P, Currey JD & Pharr GM. (1999). Variations in the individual thick lamellar properties within osteons by nanoindentation. Bone, 25(3)
- Taylor M, Verdonschot N, Huiskes R & Zioupos P. (1999). A combined finite element method and continuum damage mechanics approach to simulate the in vitro fatigue behavior of human cortical bone. Journal of Materials Science: Materials in Medicine, 10(12)
- Zioupos P, Burr DB, Turner C, Forwood MR & Pidaparti R. (1999). Correspondence. Journal of Biomechanics, 32(2)
- Rogers KD & Zioupos P. (1999). Bone tissue of the rostrum of a Mesoplodon densirostris whale: A mammalian biomineral demonstrating extreme texture. Journal of Materials Science Letters, 18(8)
- Zioupos P & Casinos A. (1998). Cumulative damage and the response of human bone in two-step loading fatigue. Journal of Biomechanics, 31(9)
- Zioupos P & Currey JD. (1998). Changes in the Stiffness, Strength, and Toughness of Human Cortical Bone With Age. Bone, 22(1)
- Rho J-Y, Kuhn-Spearing L & Zioupos P. (1998). Mechanical properties and the hierarchical structure of bone. Medical Engineering & Physics, 20(2)
- Zioupos P. (1998). Recent developments in the study of failure of solid biomaterials and bone: ‘fracture’ and ‘pre-fracture’ toughness. Materials Science and Engineering: C, 6(1)
- Zioupos P, Currey JD & Hamer A. (1998). Age changes in stiffness, strength, toughness and collagen properties of human bone. Journal of Biomechanics, 31
- Zioupos P, Currey JD, Casinos A & De Buffrénil V. (1997). Mechanical properties of the rostrum of the whale Mesoplodon densirostris, a remarkably dense bony tissue. Journal of Zoology, 241(4)
- Currey JD, Brear K & Zioupos P. (1997). The effects of ageing and changes in mineral content in degrading the toughness of human femora. Journal of Biomechanics, 30(9)
- Zioupos P, Wang XT & Currey JD. (1996). The accumulation of fatigue microdamage in human cortical bone of two different ages in vitro. Clinical Biomechanics, 11(7)
- Zioupos P, Wang XT & Currey JD. (1996). Experimental and theoretical quantification of the development of damage in fatigue tests of bone and antler. Journal of Biomechanics, 29(8)
- Currey JD, Brear K & Zioupos P. (1996). The effects of ageing and changes in mineral content in degrading the toughness of human femora. Journal of Biomechanics, 29(2)
- Zioupos P & Currey JD. (1996). Pre-failure toughening mechanisms in the dentine of the narwhal tusk: microscopic examination of stress/strain induced microcracking. Journal of Materials Science Letters, 15(11)
- Currey JD, Brear K, Zioupos P & Reilly GC. (1995). Effect of formaldehyde fixation on some mechanical properties of bovine bone. Biomaterials, 16(16)
- Zioupos P, Currey JD, Mirza MS & Barton DC. (1995). Experimentally determined microcracking around a circular hole in a flat plate of bone: comparison with predicted stresses. Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 347(1322)
- Zioupos P & Currey JD. (1994). Comments on ‘On the relationship between the microstructure of bone and its mechanical stiffness’. Journal of Biomechanics, 27(7)
- Currey JD, Brear K & Zioupos P. (1994). Dependence of mechanical properties on fibre angle in narwhal tusk, a highly oriented biological composite. Journal of Biomechanics, 27(7)
- Zioupos P & Barbenel JC. (1994). Mechanics of native bovine pericardium. Biomaterials, 15(5)
- Zioupos P & Barbenel JC. (1994). Mechanics of native bovine pericardium. Biomaterials, 15(5)
- Zioupos P, Barbenel JC & Fisher J. (1994). Anisotropic elasticity and strength of glutaraldehyde fixed bovine pericardium for use in pericardial bioprosthetic valves. Journal of Biomedical Materials Research, 28(1)
- Zioupos P & Currey JD. (1994). The extent of microcracking and the morphology of microcracks in damaged bone. Journal of Materials Science, 29(4)
- Zioupos P, Barbenel JC, Lowe GDO & MacRury S. (1993). Foot microcirculation and blood rheology in diabetes. Journal of Biomedical Engineering, 15(2)
- Zioupos P, Barbenel JC, Fisher J & Wheatley DJ. (1993). Changes in the mechanical properties of bioprosthetic valve leaflets made of bovine pericardium, as a result of long-term mechanical conditioning in vitro and implantation in vivo. Journal of Materials Science: Materials in Medicine, 4(6)
- Zioupos P, Barbenel JC & Fisher J. (1992). Mechanical and optical anisotropy of bovine pericardium. Medical & Biological Engineering & Computing, 30(1)
- Adams GJ, Cook RB, Gibson M & Zioupos P. Predicting the Fracture Toughness of Human Cancellous Bone in Fractured Neck of Femur Patients Using Bone Volume and Micro-Architecture. Life, 14(4)
- Zioupos ME. The Diabetes Epidemic in the South Pacific: A Pilot Study Utilising Hand Grip Strength in Tonga. Archives of Diabetes & Obesity, 2(1)
Conference Papers
- Appleby-Thomas GJ, Ullah Khan I, Painter J, Zioupos P, Lordachescu A, .... (2023). Characterisation of human tissues analogues for ballistic testing
- McGivern H, Greenwood C, Marquez-Grant N & Zioupos P. (2018). Getting to the bare bones of the age –related changes to the mechanical and structural properties of the clavicle
- Greenwood C, Clement J, Dicken A, Evans P, Lyburn I, .... (2018). Osteoporosis Conference 2018 Birmingham, UK 2 – 4 December 2018 Abstracts
- Franceskides C, Arnold E, Horsfall I, Clasper J, Tozzi G, .... (2017). 3D printing, the future of cost effective biomechanical testing
- Vidal B, Cascão R, Finnilä M, Lopes I, Saarakkala S, .... (2017). AB0098 Effects of tofacitinib in early arthritis bone loss
- Vidal B, Cascão R, Finnilä M, Lopes I, Saarakkala S, .... (2017). FRI0051 Early arthritis induces disturbances at bone nanostructural level reflected in decreased tissue hardness
- Shanker T, Franceskides C, Gibson M, Clasper J, Adams G, .... (2016). Effects of μCT and FE resolution in expressing anisotropic properties in vertebral cancellous bone
- Greenwood C, Rogers K, Dicken A, Evans P, Clement J, .... (2016). World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2016): Poster Abstracts
- Franceskides C, Leger T, Horsfall I, Shanker T, Adams GJ, .... (2016). Evaluation of bone excision on occipital area of simulated human skull
- Greenwood C, Clement JG, Dicken AJ, Evans JPO, Lyburn ID, .... (2016). Fracture toughness of the cancellous bone of FNF femoral heads in relation to its microarchitecture
- Bonicelli A, Zioupos P, Xhemali B & Kranioti EF. (2016). Determining ‘Age at Death’: a new multidisciplinary laboratory method based on ribs
- Wood D, Appleby-Thomas G, Fitzmaurice B, Franceskides C, Shanker T, .... (2016). On the shock behaviour and response of Ovis Aries vertebrae
- Adams GK, Cook RB & Zioupos P. (2016). Predictions for the fracture toughness of cancellous bone of fracture neck of femur patients
- Zioupos P. (2016). Forensic evidence from Bone
- Gibson MC, Franceskides C & Zioupos P. (2016). Simulated impact response of a 3-D printed skull, with an ellipsoidal excision, using finite element analysis
- Dicken AJ, Evans JPO, Rogers K, Greenwood C, Godber X, .... (2016). TOWARDS POINT OF CARE INSTRUMENTATION FOR ACCURATE FRACTURE RISK PREDICTION
- Mohamad NS, Tong J, Gorecki D, Guille M & Zioupos P. (2015). Morphological, mechanical and bone tissue properties of DMD and treated mouse bones
- Adams G, Cook RB, Greenwood C, Rogers KD & Zioupos P. (2015). Fracture toughness of cancellous bone: predictions from micro-CT values
- Adams G, Cook RB, Hutchinson J & Zioupos P. (2015). Micro-CT values versus material properties of bone over a very broad range of mineralisation levels
- Dall'Ara E, Grabowski P, Zioupos P & Viceconti M. (2015). Bone anisotropy measured with Depth sensing Micro-Indentation and Reference Point Indentation
- Franceskides C, Shanker T, Gibson M, Clasper J & Zioupos P. (2015). Input Optimisation for FEA of trabecular bone anisotropy in human thoracic-lumbar vertebrae
- Hudson R, Moniruzzaman M, Zioupos P & Gill P. (2015). Investigation of reduced sensitivity RDX
- Zioupos P. (2015). High strain rate effects and brittleness of bone and what the biophysical nature of bone can tell us for the effects observed at the macro-scale
- Adams G, Cook R, Hutchinson J & Zioupos P. (2015). The importance of thresholding in micro-CT for the histomorphometric analysis of mammalian bone tissue
- Adams G, Cook R, Hutchinson J & Zioupos P. (2014). Bone surface distribution across a wide porosity range in mammalian bone tissue
- Armstrong JR, Greenwood C, Rogers KD & Zioupos P. (2014). Assessment of the physicochemical modifications to bone mineral caused by storage protocols
- Crawford SR, Burden A, Yates JM, Zioupos P & Winwood K. (2014). The relationship between sex and age on mandibular bone mineral density and key anatomical sites as a potential key indicator for the use of facial sports protection
- Crawford SR, Burden AM, Yates JM, Zioupos P & Winwood K. (2014). OC1 Facial Bone Mineral Density: A Potential Indicator For At Risk Injury Groups
- Zioupos P & Kirchner HO. (2014). Fracture of human bone from the biophysical level: the strain rate dependent ductile to brittle transition that shifts with age is linked to transient effects for stress relaxation of the bone collagen and mineral
- Finnilä⁎ MAJ, Herlin M, Aula A, Zioupos P, Risteli J, .... (2012). TCDD-induced modulation of cortical and trabecular bone tissue is dependent on the aryl hydrocarbon receptor
- Finnilä MAJ, Herlin M, Zioupos P, Risteli J, Miettinen HM, .... (2011). Gender-specific modulation of bone remodelling by 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure and ablation of aryl hydrocarbon receptor alters material properties of bone matrix
- Dziubak A, House C, Taylor R, Cobley R, Minnock E, .... (2011). Surgeon General's Armed Forces Feeding Project: body composition and dietary intake of Royal Navy recruits
- Zioupos P, Cook R & Coats AM. (2008). Bone quality issues an matrix properties in OP cancellous bone.
- Zioupos P. (2007). Material Property Changes in Osteoporotic Cancellous Bone
- Peterlik H, Puchegger S, Rennhofer H, Loidl D, Stoll J, .... (2006). Relaxation of human bone at the nanoscale
- Peterlik H, Puchegger S, Rennhofer H, Loidl D, Stoll J, .... (2006). Relaxation of human bone at the nanoscale
- Cook RB, Zioupos P, Curwen C & Tasker T. (2006). Cancellous fracture toughness and compressive properties at the head of the femur vs. peripheral quantitative ultrasound measurements
- Zioupos P. (2006). Determination of "age at death" by laboratory based analytical methods for forensic purposes using human bone"
- Zioupos P, Cook R, Collins D & Tucker J. (2006). The predictive ability of two quantitative Ultrasound Bone scanners in comparison to DXA
- Zioupos P, Kaffy C & Currey JD. (2006). Tissue heterogeneity, composite architecture and fractal dimension effects in the fracture of ageing human bone
- Zioupos P, Christodoulou G, Giles R & Williams A. (2005). A Laboratory method to determine 'age of death' for forensic purposes using human bone
- Zioupos P, Christodoulou G, Giles R & Williams A. (2005). An Analytical Method to determine 'Age of Death' for Forensic Purposes using Human Bone
- P Z. (2005). In vivo fatigue microcracks in human bone: Material properties of the surrounding bone matrix
- Zioupos P. (2005). Age related changes of bone's material properties
- Hardy R, Watson J, Frampton R, Page M, Zioupos P, .... (2005). BOSCOS - Development and benefits of a Bone Scanning system
- Alba-Fernandez C, Casinos A & Zioupos P. (2005). Mechanics of cancellous bone in dolphins
- Zioupos P. (2004). Assessment of bone matrix at sites of in-vivo fatigue microcracks by nanoindentation
- Zioupos P & Winwood K. (2004). Rates of Development of elastic and plastic strains during fatigue of human cortical bone in tension, compression and shear
- Zioupos P, Hardy R, Watson J & Cook R. (2004). BOSCOS - Bone Scanning for Occupant Safety
- Zioupos P, Blythe A & Tasker T. (2004). Mechanical performance and reliability of two different methods of suturing semitendinosus grafts for ACL reconstructions
- Zioupos P, Alba-Fernandez C & Casinos A. (2004). Nanoindentation characterization of dolphin bones: a possible model for osteoporosis?
- Zioupos P, Cook RB & Collins D. (2004). Comparison of Patient Screening Techniques for Dual-Energy X-Ray Absorptiometry (DXA)
- Zioupos P & Currey JD. (2004). Notch sensitivity of vertebrate mineralised tissues in impact: an adaptive reason for a lower limit of mineralisation?
- Zioupos P, Gresle M & Winwood K. (2004). Microstructural and physical characteristics effects on the fatigue strength of human cortical bone
- Zioupos P, Cotton JR, Winwood K & Taylor M. (2003). Relationship between cycles to failure and rates of damage and creep in fatigue tests of human cortical bone
- Zioupos P, Blythe A & Tasker TPB. (2003). Mechanical Performance of Two Different Methods of Suturing Semitendinosus Grafts for Anterior Cruciate Ligament Reconstruction
- Zioupos P, Cook R, Collins D & Curwen C. (2003). Comparison of inter-site bone densitometry measurements and the short-term precision of two bone quantitative ultrasound scanners
- Zioupos P, Blythe A & Tasker TPB. (2003). Mechanical Performance of Two Different Methods of Suturing Semitendinosus Grafts for Anterior Cruciate Ligament Reconstruction
- Zioupos P, Fernandez C & Casinos A. (2003). Geometry and mechanics in dolphin bones. A possible model for osteoporosis
- Zioupos P, Cotton JR, Winwood K & Taylor M. (2002). Creep formulation of strain accumulation during tensile fatigue of cortical bone
- Zioupos P, Casinos A & Winwood K. (2002). In-plane shear strength and fatigue damage properties of laminar bone
- Zioupos P, Winwood K, Cotton J & Taylor M. (2002). The development of elastic and 'plastic' strains during fatigue damage accumulation of human cortical bone
- Zioupos P, Aspden RM & Coats AM. (2002). Material property issues in OP cancellous bone
- Zioupos P, Cotton JR, Winwood K & Taylor M. (2002). Nonlinear damage Theory applied to two-step fatigue failure prediction of bone.
- Taylor M, Cotton J & Zioupos P. (2002). Finite element simulation of the fatigue behaviour of cancellous bone
- Zioupos P, Winwood K & Wise V. (2001). Material property changes in bovine bone following various physicochemical treatments
- Zioupos P, Cotton JR & Taylor M. (2001). Simulation of Material Property Evolution of Cortical Bone in Fatigue Bending and its Implications on Cancellous Bone
- Zioupos P, Winwood K, Cotton J & Taylor M. (2001). Measurements of 'plastic and elastic strains during tension or compression fatigue of ageing human cortical bone.
- Zioupos P, Winwood K, Rogers KD & Wise V. (2001). Mechanical and Material property changes in bovine cortical bone subject to various physicochemical treatments
- Zioupos P, Cotton J, Winwood K, Anderson P & Taylor M. (2001). Static FEA of cortical bone tensile test samples with variations in modulus identified from micro-CT scans.
- Zioupos P, Taylor M & Cotton J. (2001). A Stochastic approach to simulate the variable fatigue life of cortical bone using combined CDM and FE method
- Zioupos P, Winwood K, Cotton JR & Taylor M. (2001). The development of 'plastic' and elastic strains in fatigue of femoral cortical bone: a possible contributor to implant failure.
- Zioupos P, Winwood K, Cotton J & Taylor M. (2001). The development of 'plastic' strains during fatigue damage accumulation
- Zioupos P, Aspden RM, Rogers KD, Noriega E & Wise V. (2001). Material quality aspects of osteoporotic cancellous bone
- Zioupos P. (2001). Accumulation of in‐vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone
- Cotton JR, Zioupos P & Taylor M. (2001). Simulated material property degradation during fatigue of human cancellous bone, as modelled by a regular honeycomb structure
- Taylor M & Zioupos P. (2001). A combined FEM and continuum damage mechanics approach to simulate the variable fatigue life of human cortical bone: A preliminary study.
- Zioupos P, Currey JD & Hamer AJ. (1999). The role of collagen in the declining mechanical properties of aging human cortical bone
- Rho JY, Zioupos P, Currey JD & Pharr GM. (1999). Mechanical properties of the individual lamellae within osteons by nanoindentation.
- Zioupos P & Rogers KD. (1999). STRUCTURAL DETAILS OF MAMMALIAN BONE MINERAL REVEALED BY RIETVELD ANALYSIS.
- Zioupos P. (1996). The accumulation of fatigue-microdamage in human cortical bone, in vitro
- Zioupos P, Currey JD & Sedman AJ. (1994). An examination of the micromechanics of failure of bone and antler by acoustic emission tests and Laser Scanning Confocal Microscopy
- Barbenel JC, Zioupos P & Fisher J. (1986). MECHANICAL PROPERTIES OF BOVINE PERICARDIUM.
Books
- Zioupos P, Currey JD & Rho JY. (2004). Bones: the need for intrinsic material and architectural design In Optimisation Mechanics in Nature, Design & Nature Series. WIT Press 2004.
- Zioupos P, Watson J, Hardy RN, Frampton O, Williams P, .... (2004). BOSCOS Bone Scanning for Occupant Safety In Special Issue of Vehicle Safety 2004. Inst. Mech. Eng. Conference, London 2004.
- Zioupos P, Smith CW & An YH. (1999). Factors affecting mechanical properties of bone In Mechanical Testing of Bone and the Bone-Implant Interface.
- Fisher J, Zioupos P, Barbenel JC & Wheatley DJ. (1989). Changes in the Material Properties and Function of Pericardial Bioprosthetic Heart Valves Invivo In Proceedings of the First International Conference on Interfaces in Medicine and Mechanics. Springer Netherlands.
- Barbenel JC, Zioupos P & Fisher J. (1988). Directional Variations in the Extensibility of Bovine Pericardium In The Influence of New Technology on Medical Practice. Macmillan Education UK.
