Contact Professor Peter Zioupos
Areas of expertise
- Ageing & Chronic Disease
- Biomedical Engineering
- Human Factors for Defence
Background
Education
DSc: Bioengineering, Faculty of Engineering,
Strathclyde University (2007); 'Composite aspects of basic bone biomechanics:
structure/function relationships and applications'.
PhD: Bioengineering, Faculty of Engineering, Strathclyde University (1989);
Tissue mechanics of Bioprosthetic heart valves.
BSc: Physics, University of Ioannina Greece (1983)
Other Websites
https://scholar.google.co.uk/citations?hl=en&user=gmGZ-8cAAAAJ
https://orcid.org/0000-0002-0123-2706
https://www.linkedin.com/in/dr-peter-zioupos-aa1126a6/
https://www.researchgate.net/profile/peter-Zioupos
https://exaly.com/author/2453455/peter-zioupos
Interests
Biomedical Engineering; Biomechanics of Materials; Ageing & Chronic Disease; Human Factors for Defence; Forensic Biomechanics;
Profile
Peter Zioupos is a Professor in Biomedical Engineering in School of Engineering in University of Hull. He has held previous appointments in the universities of Cranfield, York and Strathclyde.
He has an interest in Musculoskeletal science and research and their link to Orthopaedic Biomechanics, Bone physiology, Bone ageing, Anatomy and Forensics.
He is a Visiting Professor of the Institute of Future Transport & Cities of Coventry University (Nov 2020) advising on automotive related trauma and applications, a Visiting Fellow in CFI at Cranfield University and also a Fellow of the IPEM (Institute of Physics and Engineering in Medicine). In 2008, he was awarded the Degree of Doctor of Science by the Senate of Strathclyde University following the recommendation by the Higher Doctorates Committee for his work on ‘Composite aspects of basic bone biomechanics: structure/function relationships and applications'. Over the past 20 years he has published over 100 peer review articles in this specialised topic, gathering over 6100 citations. 13 papers, in particular, are now ‘classics' in the field of basic bone biomechanics with more than 100 citations each.
He is in the Editorial advisory board of the Journal of Biomechanics (ELSEVIER) and the Editorial boards of the Journal of Mechanical Behaviour of Biomedical Materials (ELSEVIER), Journal of Bionic Engineering (SPRINGER), Frontiers in Bioengineering and Biotechnology (section Biomechanics) and LIFE (MDPI) and LIFE (MDPI). He was the guest editor for a Special issue of the 'Journal of Mechanical Behavior of Biomedical Materials' on ‘Forensic Biomechanics’ (May 2014) which presents a good choice of papers across a range of applications in the field of Medicolegal Biomechanics.
Publishing opportunities
Peter Zioupos is presently compiling a special issue in LIFE called: "Hard and Soft Tissue Biomechanics ‘In Translation’" to which papers are now invited for submission https://www.mdpi.com/journal/life/special_issues/Y4Q28H3138. The Special issue topics are: (1) Biomechanics of cells, tissues, and biomaterials; (2) Hard–soft tissue interface; (3) Bioinspired 3D printed and electro-spun materials; (4) Imaging-based mechanics of tissues and biomaterials; (5) Deep learning and computational modelling; (6) Other techniques with the potential to complement, inform, and expand knowledge of hard and soft tissues.
Current activities
His most recent work was in detecting the arrival of ‘maturity’ in the human skeleton by biomechanical and physicochemical methods (BONE in 2022) and on the influence of varying strain rate on the properties of bone (BONE in 2020). In the latter a paradigm shifting paper he has shown that the fragility of ageing bone in particular is a result of a ductile-to-brittle-transition (DBT) which shifts to lower strain rates for older individuals. The cause of this effect is biophysical in its nature and shows that the so called 'bone properties' can only be understood in the context of its history and its environment both mechanical and ambient. The content and context of this new way of looking at bone fracture as a 'dynamic' material which experiences failure in a 'stochastic' manner were presented in a special issue of the journal BONE https://www.sciencedirect.com/journal/bone/special-issue/10VZ6CMZR77 and in a WEBINAR (19 Nov 2020) given in memory of the late John D Currey for JMBBM (J Mechanical Properties of Biomedical Materials) YouTube: https://youtu.be/BuYBImaAc28
PZ is also active in forensics and offers consultancy in legal cases regarding lethal or otherwise trauma, which involves primarily bone injuries. He has developed a patent for the Forensic determination of age at time of death by analytical laboratory examination of bone matrix. He offers consultancy to industry via nanoindentation studies on various health care products, on anodising layers, design of test chambers and testing standards. He has appeared in TV documentaries: one for Discovery Channel on "free fall" accidents, and in National Geographic on the circumstances surrounding the unexpected "death of King Tutankhamen". A more recent presentation was in BBC2 the 'AUTUMNWATCH' programme (31 October 2019). Peter was interviewed on the comparative properties of bone and antler material. A structure/function link was made on screen between the gross anatomy and material properties of these two very different kinds of bone and their function/performance in life.
Publications
Articles In Journals
- Maier AK, Manzella A, Bonicelli A, Arnold EL, Márquez-Grant N & Zioupos P (2023) Wet bone characteristics persist in buried bone after 10 weeks: implications for forensic anthropology, Forensic Sciences, 3 (3) 491-505.
- Walden SJ, Rowe W, Mulville J, Evans SL & Zioupos P (2023) Quantifying microcracks on fractured bone surfaces – Potential use in forensic anthropology, Journal of the Mechanical Behavior of Biomedical Materials, 142 (June) Article No. 105824.
- Bonicelli A, Tay T, Cobb JP, Boughton OR, Hansend U, Abel RL & Zioupos P (2023) Association between nanoscale strains and tissue level nanoindentation properties in age-related hip-fractures, Journal of the Mechanical Behavior of Biomedical Materials, 138 (February) Article No. 105573.
- Berli ME, Franco F, Di Paolo J, Zioupos P & Borau C (2022) The interplay between BMU activity linked to mechanical stress, specific surface and inhibitory theory dictate bone mass distribution: predictions from a 3D computational model, Computers in Biology and Medicine, 148 (September) Article No. 105898.
- Bonicelli A, Kranioti EF, Xhemali B, Arnold E & Zioupos P (2022) Assessing bone maturity: compositional and mechanical properties of rib cortical bone at different ages, Bone, 155 (February) Article No. 116265.
- Adams GJ, Cook RB, Hutchinson JR & Zioupos P (2022) Microarchitecture and morphology of bone tissue over a wide range of BV/TV assessed by micro-computed tomography and three different threshold backgrounds, Medical Engineering and Physics, 106 (August) Article No. 103828. Dataset/s: 10.17862/cranfield.rd.20015906
- Bastien C, Neal-Sturgess C, Davies H, Hardwicke J, Cloake T & Zioupos P (2021) A generic brain trauma computer framework to assess brain injury severity and bridging vein rupture in traumatic falls, Journal of Head Neck & Spine Surgery, 4 (4) 47-60.
- Bonicelli A, Zioupos P, Arnold E, Rogers K, Xhemali B & Kranioti EF (2021) Age related changes of rib cortical bone matrix and the application to forensic age-at-death estimation, Scientific Reports, 11 (1) Article No. 2086. Dataset/s: 10.1038/s41598-021-81342-0/MediaObjects/41598_2021_81342_MOESM1_ESM.docx
- Franceskides C, Gibson M & Zioupos P (2020) Evaluation of bone excision effects on a human skull model - II: Finite element analysis., Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 234 (4) 346-355.
- Franceskides C, Arnold E, Horsfall I, Tozzi G, Gibson MC & Zioupos P (2020) Spinal motion segments — II: tuning and optimisation for biofidelic performance, Journal of Bionic Engineering, 17 (4) 757-766.
- Franceskides C, Arnold E, Horsfall I, Tozzi G, Gibson MC & Zioupos P (2020) Spinal motion segments — I: concept for a subject-specific analogue model, Journal of Bionic Engineering, 17 (4) 747-756.
- McGivern H, Greenwood C, Marquez-Grant N, Kranioto EF, Xhemali B & Zioupos P (2020) Age-related trends in the trabecular micro-architecture of the medial clavicle: is it of use in forensic science?, Frontiers in Bioengineering and Biotechnology, 7 (January) Article No. 467. Dataset/s: 10.17862/cranfield.rd.11673606.v1
- Franceskides C, Leger T, Horsfall I, Tozzi G, Gibson M & Zioupos P (2020) Evaluation of bone excision effects on a human skull model - I: Mechanical testing and digital image correlation, Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, 234 (4) 337-345.
- Zioupos P, Kirchner HOK & Peterlik H (2020) Ageing bone fractures: the case of a ductile to brittle transition that shifts with age, Bone, 131 (February) Article No. 115176.
- Currey JD, Brear K & Zioupos P (2019) Strain rate dependence of work of fracture tests on bone and similar tissues: reflections on testing methods and mineral content effects., Bone, 128 (November) Article No. 115038.
- Zioupos ME, Takai J, Ahmad J & Zioupos P (2019) The diabetes epidemic in the South Pacific: a pilot study utilising hand grip strength in Tonga, Archives of Diabetes and Obesity, 2 (1) 118-128.
- Vidal B, Cascão R, Finnilä MAJ, Lopes IP, da Glória VG, Saarakkala S, Zioupos P, Canhão H & Fonseca JE (2018) Effects of tofacitinib in early arthritis-induced bone loss in an adjuvant-induced arthritis rat model, Rheumatology (Oxford), 57 (8) 1461-1471.
- Greenwood C, Clement J, Dicken A, Evans P, Lyburn I, Martin RM, Stone N, Zioupos P & Rogers K (2018) Age-related changes in femoral head trabecular microarchitecture, Aging and Disease, 9 (6) 976-987.
- Mooring L, Thompson S, Hall SA, Pani S, Zioupos P, Swan M, Stone C, Howlin BJ & Hamerton I (2018) ‘Phoenix polymers’: fire induced nanohardness in fibril-forming aromatic cyanate esters, RSC Advances, 8 (63) 36264-36271.
- Vidal B, Cascão R, Finnilä MAJ, Lopes IP, Saarakkala S, Zioupos P, Canhão H & Fonseca JE (2018) Early arthritis induces disturbances at bone nanostructural level reflected in decreased tissue hardness in an animal model of arthritis., PLoS ONE, 13 (1) 1-16.
- Adams GJ, Cook RB, Hutchinson JR & Zioupos P (2018) Bone apparent and material densities examined by cone beam computed tomography and the Archimedes technique: comparison of the two methods and their results, Frontiers in Mechanical Engineering, 3 (23).
- Bonicelli A, Xhemali B, Kranioti EF & Zioupos P (2017) Rib biomechanical properties exhibit diagnostic potential for accurate ageing in forensic investigations, PLoS ONE, 12 (5) Article No. e0176785.
- Macoveciuc I, Marquez-Grant N, Horsfall I & Zioupos P (2017) Sharp and blunt force trauma concealment by thermal alteration in homicides: an in-vitro experiment for methodology and protocol development in forensic anthropological analysis of burnt bones, Forensic Science International, 275 (June) 260-271.
- Berli. M, Borau C, Decco O, Adams G, Cook RB, García Aznar JM & Zioupos P (2017) Localized tissue mineralization regulated by bone remodelling: a computational approach, PLoS ONE, 12 (3) Article No. e0173228.
- Dicken AJ, Evans JPO, Rogers K, Greenwood C, Godber X, Stone N, Clement J, Lyburn I, Martin R & Zioupos P (2016) Towards point of care instrumentation for accurate fracture risk prediction, Osteoporosis International, 27 S148-S148.
- Mohamad NS, Sinadinos A, Górecki DC, Zioupos P & Tong J (2016) Impact of P2RX7 ablation on the morphological, mechanical and tissue properties of bones in a murine model of duchenne muscular dystrophy, Journal of Biomechanics, 49 (14) 3444-3451.
- Greenwood C, Clement J, Dicken A, Evans J, Lyburn I, Martin R, Rogers K, Stone N & Zioupos P (2016) Towards new material biomarkers for fracture risk, Bone, 93 (December) 55-63.
- Dicken AJ, Evans JP, Rogers KD, Stone N, Greenwood C, Godber SX, Clement JG, Lyburn ID, Martin RM & Zioupos P (2016) Classification of fracture and non-fracture groups by analysis of coherent X-ray scatter, Scientific Reports, 6 (1) Article No. 29011.
- Greenwood C., Clement J., Dicken A., Evans J., Lyburn I., Martin R., Rogers K., Stone N., Adams G. & Zioupos P. (2015) The micro-architecture of human cancellous bone from fracture neck of femur patients in relation to the structural integrity and fracture toughness of the tissue, Bone Reports, 3 67-75.
- Crawford S., Burden A., Yates J., Zioupos P. & Winwood K. (2015) Can masticatory electromyography be normalised to submaximal bite force?, Journal of Oral Rehabilitation, 42 (5) 323-330.
- Dall'Ara E, Grabowski P, Zioupos P & Viceconti M (2015) Estimation of local anisotropy of plexiform bone: comparison between depth sensing micro-indentation and Reference Point Indentation, Journal of Biomechanics, 48 (15) 4073-4080.
- Dicken A., Evans J., Rogers K., Stone N., Greenwood C., Godber S., Prokopiou D., Clement J., Lyburn I., Martin R. & Zioupos P. (2015) X-ray diffraction from bone employing annular and semi-annular beams, Physics in Medicine and Biology, 60 (15) 5803-5812.
- Dicken A. J., Evans J. P. O., Rogers K. D., Greenwood C., Godber S. X., Prokopiou D., Stone N., Clement J. G., Lyburn I., Martin R. M. & Zioupos P. (2015) Energy-dispersive X-ray diffraction using an annular beam, Optics Express, 23 (10) 13443-13454.
- Zioupos P, Williams A, Christodoulou G & Giles R (2014) Determining 'age at death' for forensic purposes using human bone by a laboratory-based biomechanical analytical method, Journal of the Mechanical Behavior of Biomedical Materials, 33 (May) 109-123.
- Zioupos P (2014) Forensic biomechanics, Journal of the Mechanical Behavior of Biomedical Materials, 33 (1) 1-2.
- Akbarzadeh J, Puchegger S, Stojanovic A, Kirchner H, Binder W, Bernstorff S, Zioupos P & Peterlik H. (2014) Timescales of self-healing in human bone tissue and polymeric ionic liquids, Bioinspired, Biomimetic and Nanobiomaterials, 3 (3) 123-130.
- Asgharpour Z, Zioupos P, Graw M & Peldschus S (2014) Development of a strain rate dependent material model of human cortical bone for computer-aided reconstruction of injury mechanisms, Forensic Science International, 236 (March) 109-116.
- Herlin M, Finnilä MAJ, Zioupos P, Aula A, Risteli J, Miettinen HM, Jämsä T, Tuukkanen J, Korkalainen M, Håkansson H & Viluksela M (2013) New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties, Toxicology and Applied Pharmacology, 273 (1) 219-226.
- Hudson RJ, Zioupos P & Gill PP (2012) Investigating the mechanical properties of RDX crystals using nano-indentation, Propellants, Explosives, Pyrotechnics, 37 (2) 191-197.
- Ural A, Zioupos P, Buchanan D & Vashishth D (2012) Evaluation of the influence of strain rate on Colles' fracture load, Journal of Biomechanics, 45 (10) 1854-1857.
- Finnila MAJ, Herlin M, Aula A, Zioupos P, Risteli J, Miettinen H, Korkalainen M, Jamsa T, Tuukkanen J, Hakansson H & Viluksela M (2012) TCDD-induced modulation of cortical and trabecular bone tissue is dependent on the aryl hydrocarbon receptor, Bone, 50 (supp 1) S128-S129.
- Ertas A H, Winwood K, Zioupos P & Cotton J R (2012) Simulation of creep in non-homogenous samples of human cortical bone., Computer Methods in Biomechanics and Biomedical Engineering, 15 (10) 1121-1128.
- Ural A, Zioupos P, Buchanan D & Vashishth D (2011) The effect of strain rate on fracture toughness of human cortical bone: a finite element study, Journal of the Mechanical Behavior of Biomedical Materials, 4 (7) 1021-1032.
- Dziubak A, House C, Taylor R, Cobley R, Minnock E, Zioupos P, Davey T & Allsopp AJ (2011) Surgeon General's Armed Forces Feeding Project: body composition and dietary intake of Royal Navy recruits, Proceedings of the Nutrition Society, 70 (OCE6).
- Finnila MAJ, Herlin M, Zioupos P, Risteli J, Miettinen HM, Korkalainen M, Jamsa T, Tuukkanen J, Hakansson H & Viluksela M (2011) Gender-specific modulation of bone remodelling by 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure and ablation of aryl hydrocarbon receptor alters material properties of bone matrix, Bone, 48.
- Cook RB, Curwen C, Tasker T & Zioupos P (2010) Fracture toughness and compressive properties of cancellous bone at the head of the femur and relationships to non-invasive skeletal assessment measurements, Medical Engineering and Physics, 32 (9) 991-997.
- Finnilä MAJ, Zioupos P, Herlin M, Miettinen HM, Simanainen U, Håkansson H, Tuukkanen J, Viluksela M & Jämsä T (2010) Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on bone material properties, Journal of Biomechanics, 43 (6) 1097-1103.
- Cook RB & Zioupos P (2010) Corrigendum to "The fracture toughness of cancellous bone": [J. Biomech. 42 (2009) 2054-2060], Journal of Biomechanics, 43 (7) 1441-1441.
- Zioupos P, Cook R B & Hutchinson J R (2009) More thoughts on the relationship between apparent and material densities in bone., Journal of Biomechanics, 42 (6) 794-5.
- Cook RB & Zioupos P (2009) The fracture toughness of cancellous bone, Journal of Biomechanics, 42 (13) 2054-2060.
- Gupta H & Zioupos P (2008) Fracture of bone tissue: the 'hows' and the 'whys', Medical Engineering and Physics, 30 (10) 1209-1226.
- Zioupos P, Hansen U, Simpson R, Currey JD & Hynd D (2008) The effect of strain rate on the biomechanical properties of Human Cortical Bone, Journal of Biomechanical Engineering, 130 (1) 11011-1.
- Zioupos P, Hutchinson JR & Cook RB (2008) Some basic relationships between density values in cancellous and cortical bone, Journal of Biomechanics, 41 (9) 1961-1968.
- Zioupos P, Hansen U & Currey JD (2008) Microcracking damage and the fracture process in relation to strain rate in human cortical bone tensile failure, Journal of Biomechanics, 41 (14) 2932-2939.
- Zioupos P, Gresle M & Winwood K (2008) Fatigue strength of human cortical bone:age physical and material heterogeneity effects, Journal of Biomedical Materials Research Part A, 86 (3) 627-636.
- Hansen U, Zioupos P, Simpson R, Currey J & Hynd D. (2008) The effect of strain rate on the mechanical properties of human cortical bone, Journal of Biomechanical Engineering, 130 (1) Article No. 011011 - .
- Zioupos P, Gresle M & Winwood K. (2008) Fatigue strength of human cortical bone: Age, physical, and material heterogeneity effects, Journal of Biomedical Materials Research Part A, 86 (3) 627-636.
- Minnock E, Cook R, Collins D, Tucker J & Zioupos P (2008) Using risk factors and quantitative ultrasound to identify postmenopausal caucasian women at risk of osteoporosis, Journal of Clinical Densitometry, 11 (4) 485-493.
- Winwood K, Zioupos P, Currey J, Cotton J & Taylor M (2006) Strain patterns during tensile, compressive, and shear fatigue of human cortical bone and implications for bone biomechanics, Journal of Biomedical Materials Research, 79A (2) 289-297.
- Zioupos P, Kaffy C & Currey JD (2006) Tissue heterogeneity, composite architecture and fractal dimension effects in the fracture of ageing human bone, International Journal of Fracture, 139 (3-4) 407-424.
- Moniruzzaman M, Zioupos P & Fernando GF (2006) Investigation of Reversible Photo-Mechanical Properties of Azobenzene-Based Polymer Films by Nanoindentation, Scripta Materialia, 42 (2) 257-261.
- Winwood K, Zioupos P, Currey JD, Cotton JR & Taylor M (2006) The importance of the elastic and plastic components of strain in tensile and compressive fatigue of human cortical bone in relation to orthopaedic biomechanics, The Journal of Musculoskeletal and Neuronal Interactions, 6 (2) 134-141.
- Blythe A, Tasker T & Zioupos P (2006) ACL graft constructs: In-vitro fatigue testing highlights the occurrence of irrecoverable lengthening and the need for adequate (pre)conditioning to avert the recurrence of knee instability., Technology and Health Care, 14 (4-5) 335-47.
- Zioupos P & Rogers KD (2006) Complementary physical and mechanical techniques to characterise tooth: a bone-like tissue, Journal of Bionic Engineering, 3 (1) 19-31.
- Zioupos P (2005) In vivo fatigue microcracks in human bone: Material properties of the surrounding bone matrix, European Journal of Morphology, 42 (1/2) 31-41.
- Zioupos P, Cotton J, Winwood K & Taylor M (2005) Damage rate is a predictor of fatigue life and creep strain rate in fatigue of tensile human cortical bone samples, Journal of Biomechanical Engineering, 127 (2) 213-219.
- Alba-Fernandez C, Casinos A & Zioupos P (2005) Mechanics of cancellous bone in dolphins, Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology, 141 (3).
- Zioupos P, Cook RB, Collins D & Tucker J (2005) The Ability of Peripheral Quantitative Ultrasound to Identify Patients with Low Bone Mineral Density in the Hip or Spine, Ultrasound in Medicine and Biology, 31 (5) 625-632.
- Zioupos P, Cook RB, Collins D & Tucker J (2005) Comparison of Questionnaire and Quantitative Ultrasound Techniques as screening tools for DXA, Osteoporosis International, 16 (12) 1565-1575.
- Currey J., Brear K. & Zioupos P. (2004) Notch sensitivity of mammalian mineralized tissues in impact, Proceedings of the Royal Society B: Biological Sciences, 271 (1538) 517-522.
- Cotton J, Winwood K, Zioupos P & Taylor M. (2004) Damage rate is a predictor of fatigue life and creep strain rate in tensile fatigue of human cortical bone samples, Journal of Biomechanical Engineering, 127 (2) 213-219.
- Zioupos P, Cotton J, Winwood K & Taylor M (2003) Analysis of creep strain during tensile fatigue of cortical bone, Journal of Biomechanics, 36 (7) 943-949.
- Zioupos P, Coats AM & Aspden RM (2003) Material properties of subchondral bone from patients with osteoporosis or osteoarthritis by microindentation testing and electron probe microanalysis, Calcified Tissue International, 73 (1) 66-71.
- Zioupos P (2002) Microstructural elasticity and regional heterogeneity in human femoral bone of various ages examined by nano-indentation, Journal of Biomechanics, 35 (2) 189-198.
- Taylor M, Cotton J & Zioupos P (2002) Finite element simulation of the fatigue behaviour of cancellous bone, Meccanica, 37 (4-5) 419-429.
- Currey J, Zioupos P, Davies P & Casinos A (2001) Mechanical properties of nacre and highly mineralized bone, Proceedings of the Royal Society B: Biological Sciences, 268 (1462) 107-111.
- Zioupos P (2001) Accumulation of in-vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone, Journal of Microscopy, 201 (2) 270-278.
- Zioupos P (2001) Ageing Human Bone: factors affecting its biomechanical properties and the role of collagen, Journal of Biomaterials Applications, 15 (3) 187-229.
- Currey JD & Zioupos P (2001) The effect of porous microstructure on the anisotropy of bone-like tissue: a counterexample, Journal of Biomechanics, 34 (5) 707-708.
- Zioupos P, Rho JY, Currey JD & Pharr GM (2001) The anisotropic Young's modulus of equine secondary osteones and interstitial bone determined by nanoindentation, Journal of Experimental Biology, 204 (10) 1775-1781.
- Zioupos P, Currey J & Casinos A. (2001) Tensile fatigue in bone: Are cycles-, or time to failure, or both, important?, Journal of Theoretical Biology, 210 (3) 389-399.
- Rho JY, Zioupos P, Currey JD & Pharr GM (2000) Response, Bone, 26 (5) 545-546.
- Zioupos P, Currey JD & Casinos A (2000) Exploring the effects of hypermineralisation in bone tissue by using an extreme biological example., Connective Tissue Research, 41 (3) 229-48.
- Rhoa JY, Zioupos P, Currey JD & Pharrd GM (2000) Letters to the editor, Bone, 26 (5) 545-546.
- Zioupos P (1999) Recent developments in the study of failure of solid biomaterials and bone: 'Fracture' and 'pre-fracture' toughness, Materials Science and Engineering C: Materials for Biological Applications, 6 (1) 33-40.
- Rho JY, Zioupos P, Currey JD & Pharr GM (1999) Variations in the individual thick lamellar properties within osteons by nanoindentation, Bone, 25 (3) 295-300.
- Rogers K. & Zioupos P. (1999) Bone tissue of the rostrum of a Mesoplodon densirostris whale: A mammalian biomineral demonstrating extreme texture, Journal of Materials Science Letters, 18 (8) 651-654.
- Taylor M, Verdonschot N, Huiskes R & Zioupos P (1999) A combined finite element method and continuum damage mechanics approach to simulate the in vitro fatigue behavior of human cortical bone, Journal of Materials Science: Materials in Medicine, 10 (12) 841-846.
- Zioupos P, Currey JD & Hamer AJ (1999) The role of collagen in the declining mechanical properties of aging human cortical bone., Journal of Biomedical Materials Research Part A, 45 (2) 108-16.
- Rho JY, Zioupos P, Currey JD & Pharr GM (1999) Mechanical properties of the individual lamellae within osteons by nanoindentation, Journal of Bone and Mineral Research, 14.
- Zioupos P (1999) On microcracks, microcracking, in-vivo, in-vitro, in-situ and other issues, Journal of Biomechanics, 32 (2) 209-211, 213-259.
- Zioupos P, Burr D, Turner C, Forwood M & Pidaparti R (1999) On microcracks, microcracking, in-vivo, in-vitro, in-situ and other issues (multiple letters), Journal of Biomechanics, 32 (2) 209-259.
- Rogers KD & Zioupos P (1999) The bone tissue of the rostrum of a Mesoplodon Densirostris whale: a mammalian biomineral demonstrating extreme texture, Journal of Materials Science Letters, 18 (8) 651-654.
- Zioupos P (1999) On microcracks, microcracking, in-vivo, in-vitro, in-situ and other issues (multiple letters), Journal of Biomechanics, 32 (2) 209-211.
- Zioupos P & Casinos A (1998) Cumulative damage and the response of human bone in two-step loading fatigue., Journal of Biomechanics, 31 (9) 825-33.
- Zioupos P & Currey JD (1998) Changes in the stiffness, strength, and toughness of human cortical bone with age., Bone, 22 (1) 57-66.
- Rho JY, Kuhn-Spearing L & Zioupos P (1998) Mechanical properties and the hierarchical structure of bone, Medical Engineering and Physics, 20 (2) 92-102.
- Zioupos P, Currey JD, Casinos A & De Buffrénil V (1997) Mechanical properties of the rostrum of the whale Mesoplodon densirostris, a remarkably dense bony tissue, Journal of Zoology, 241 (4) 725-737.
- Currey JD, Brear K & Zioupos P (1997) Erratum: The effects of ageing and changes in mineral content in degrading the toughness of human femora (Journal of Biomechanics (1996) 29 (257-260)), Journal of Biomechanics, 30 (9) 1001-1001.
- Currey JD, Brear K & Zioupos P (1996) The effects of ageing and changes in mineral content in degrading the toughness of human femora, Journal of Biomechanics, 29 (2) 257-260.
- Zioupos P, Wang XT & Currey JD (1996) The accumulation of fatigue microdamage in human cortical bone of two different ages in vitro, Clinical Biomechanics, 11 (7) 365-375.
- Zioupos P, Wang XT & Currey JD (1996) Experimental and theoretical quantification of the development of damage in fatigue tests of bone and antler, Journal of Biomechanics, 29 (8) 989-1002.
- Zioupos P & Currey JD (1996) Pre-failure toughening mechanisms in the dentine of the narwhal tusk: Microscopic examination of stress/strain induced microcracking, Journal of Materials Science Letters, 15 (11) 991-994.
- Currey JD, Brear K, Zioupos P & Reilly GC (1995) Effect of formaldehyde fixation on some mechanical properties of bovine bone, Biomaterials, 16 (16) 1267-1271.
- Zioupos P, Currey JD, Mirza MS & Barton DC (1995) Experimentally determined microcracking around a circular hole in a flat plate of bone: comparison with predicted stresses., Philosophical transactions of the Royal Society of London. Series B: Biological sciences, 347 (1322) 383-396.
- Currey JD, Brear K & Zioupos P (1994) Dependence of mechanical properties on fibre angle in narwhal tusk, a highly oriented biological composite, Journal of Biomechanics, 27 (7) 885-897.
- Zioupos P & Currey JD (1994) Comments on 'On the relationship between the microstructure of bone and its mechanical stiffness', Journal of Biomechanics, 27 (7) 993-994.
- Zioupos P & Barbenel JC (1994) Mechanics of native bovine pericardium. II. A structure based model for the anisotropic mechanical behaviour of the tissue, Biomaterials, 15 (5) 374-382.
- Zioupos P, Barbenel JC & Fisher J (1994) Anisotropic elasticity and strength of glutaraldehyde fixed bovine pericardium for use in pericardial bioprosthetic valves, Journal of Biomedical Materials Research, 28 (1) 49-57.
- Zioupos P, Currey JD & Sedman AJ (1994) An examination of the micromechanics of failure of bone and antler by acoustic emission tests and Laser Scanning Confocal Microscopy, Medical Engineering and Physics, 16 (3) 203-212.
- Zioupos P & Barbenel JC (1994) Mechanics of native bovine pericardium. I. The multiangular behaviour of strength and stiffness of the tissue, Biomaterials, 15 (5) 366-373.
- Zioupos P (1994) The extent of microcracking and the morphology of microcracks in damaged bone, Journal of Materials Science, 29 (4) 978-986.
- Zioupos P, Barbenel JC, Lowe GDO & MacRury S (1993) Foot microcirculation and blood rheology in diabetes, Journal of Biomedical Engineering, 15 (2) 155-158.
- Zioupos P, Barbenel JC, Fisher J & Wheatley DJ (1993) Changes in the mechanical properties of bioprosthetic valve leaflets made of bovine pericardium, as a result of long-term mechanical conditioning in vitro and implantation in vivo, Journal of Materials Science: Materials in Medicine, 4 (6) 531-537.
- Zioupos P, Barbenel JC & Fisher J (1992) Mechanical and optical anisotropy of bovine pericardium, Medical and Biological Engineering and Computing, 30 (1) 76-82.
- Sedman AJ, Currey JD & Zioupos P Optical changes associated with microdamage in bone, antler and narwhal tusk, BONE.
Conference Papers
- Appleby-Thomas GJ, Ullah Khan I, Painter J, Zioupos P, Lordachescu A & Hes RAG (2023) Characterisation of human tissues analogues for ballistic testing. In: 56th UK Human Responses to Vibration Conference, 2023, Institute of Naval Medicine, Gosport, 29-30 August 2023.
- Greenwood C, Clement J, Dicken A, Evans P, Lyburn I, Martin R, Stone N, Zioupos P & Rogers K (2018) Point-of-care high accuracy fracture risk prediction for osteoporosis. In: Osteoporosis Conference 2018, Birmingham, 2-4 December 2018.
- McGivern H, Greenwood C, Marquez-Grant N & Zioupos P (2018) Getting to the bare bones of the age –related changes to the mechanical and structural properties of the clavicle. In: Bone Research Society (BRS) Annual Meeting, Stripe Building, King Alfred Campus, University of Winchester, Winchester, 27-29 June 2018.
- Franceskides C, Arnold E, Horsfall I, Clasper J, Tozzi G & Zioupos P (2017) 3D printing, the future of cost effective biomechanical testing. In: SAFE Europe Symposium 2017, Amsterdam, 3-6 April 2017.
- Bonicelli A, Zioupos P, Xhemali B & Kranioti EF (2016) Determining ‘Age at Death’: a new multidisciplinary laboratory method based on ribs. In: 22nd Congress of the European Society of Biomechanics (ESB 2016), Lyon, 10-13 July 2016.
- Gibson MC, Franceskides C & Zioupos P (2016) Simulated impact response of a 3-D printed skull, with an ellipsoidal excision, using finite element analysis. In: 22nd Congress of the European Society of Biomechanics (ESB 2016), Lyon, 10-13 July 2016.
- Greenwood C, Clement JG, Dicken AJ, Evans JPO, Lyburn ID, Martin RM, Rogers KD, Stone N, Adams G & Zioupos P (2016) Fracture toughness of the cancellous bone of FNF femoral heads in relation to its microarchitecture. In: 22nd Congress of the European Society of Biomechanics (ESB 2016), Lyon, 10-13 July 2016.
- Adams GK, Cook RB & Zioupos P (2016) Predictions for the fracture toughness of cancellous bone of fracture neck of femur patients. In: 22nd Congress of the European Society of Biomechanics (ESB 2016), Lyon, 10-13 July 2016.
- Wood D, Appleby-Thomas G, Fitzmaurice B, Franceskides C, Shanker T, Zioupos P & Samra A (2016) On the shock behaviour and response of Ovis Aries vertebrae. In: 22nd Congress of the European Society of Biomechanics (ESB 2016), Lyon, 10-13 July 2016.
- Zioupos P (2016) Forensic evidence from Bone. In: Forensics Europe EXPO, London, 19-20 April 2016.
- Shanker T, Franceskides C, Gibson M, Clasper J, Adams G & Zioupos P (2016) Effects of μCT and FE resolution in expressing anisotropic properties in vertebral cancellous bone. In: 51st UK Conference on Human Responses to Vibration, Gosport, 14-15 September 2016.
- Greenwood C, Rogers K, Dicken A, Evans P, Clement J, Lyburn I, Martin R, Zioupos P & Stone N (2016) Bone ultrastructure and architecture: the role of bone quality in fracture prediction. In: World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases, Malaga, 14-16 April 2016.
- Franceskides C, Leger T, Horsfall I, Shanker T, Adams GJ , Clasper J & Zioupos P (2016) Evaluation of bone excision on occipital area of simulated human skull. In: 22nd Congress of the European Society of Biomechanics (ESB 2016), Lyon, 10-13 July 2016.
- Hudson R, Moniruzzaman M, Zioupos P & Gill P (2015) Investigation of reduced sensitivity RDX. In: 2nd International Workshop on Advances in Solid Propellant Systems (IWAPS 2015), Pune, 12-13 March 2015.
- Dall'Ara E, Grabowski P, Zioupos P & Viceconti M (2015) Bone anisotropy measured with Depth sensing Micro-Indentation and Reference Point Indentation. In: 21st Congress of the European Society of Biomechanics, Prague, 5 July 2015.
- Adams G, Cook RB, Hutchinson J & Zioupos P (2015) Micro-CT values versus material properties of bone over a very broad range of mineralisation levels. In: 21st Congress of the European Society of Biomechanics, Prague, 5 July 2015.
- Mohamad NS, Tong J, Gorecki D, Guille M, Zioupos P, (2015) Morphological, mechanical and bone tissue properties of DMD and treated mouse bones. In: 21st Congress of the European Society of Biomechanics, Prague, 5 July 2015.
- Adams, G, Cook RB, Greenwood C, Rogers KD & Zioupos P (2015) Fracture toughness of cancellous bone: predictions from micro-CT values. In: 21st Congress of the European Society of Biomechanics, Prague, 5 July 2015.
- Franceskides C, Shanker T, Gibson M, Clasper J & Zioupos P (2015) Input Optimisation for FEA of trabecular bone anisotropy in human thoracic-lumbar vertebrae. In: 13th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Montreal, 1 September 2015.
- Zioupos P (2015) High strain rate effects and brittleness of bone and what the biophysical nature of bone can tell us for the effects observed at the macro-scale. In: XXV Congress of the International Society of Biomechanics, Glasgow, 12 July 2015.
- Adams G, Cook R, Hutchinson J & Zioupos P (2015) The importance of thresholding in micro-CT for the histomorphometric analysis of mammalian bone tissue. In: XXV Congress of the International Society of Biomechanics, Glasgow, 12 July 2015.
- Crawford SR., Burden A, Yates JM, Zioupos P, Winwood K, (2014) Facial Bone Mineral Density: A potential indicator for at risk injury groups. In: International Sports Science + Sports Medicine, Newcastle-Upon-Tyne, 19-21 August 2014.
- Adams G, Cook R, Hutchinson J, Zioupos P, (2014) Bone surface distribution across a wide porosity range in mammalian bone tissue. In: 7th World Congress of Biomechanics (WCB 2014), Boston, 6 July 2014.
- Zioupos P, Kirchner HO, (2014) Fracture of human bone from the biophysical level: the strain rate dependent ductile to brittle transition that shifts with age is linked to transient effects for stress relaxation of the bone collagen and mineral. In: 6th Conference Elemvio, Patras, 10 October 2014.
- Crawford SR, Burden A, Yates JM, Zioupos P & Winwood K (2014) The relationship between sex and age on mandibular bone mineral density and key anatomical sites as a potential key indicator for the use of facial sports protection. In: Bone Research Society Annual Meeting 2014, Sheffield, 25 June 2014.
- Armstrong JR, Greenwood C, Rogers KD & Zioupos P (2014) Assessment of the physicochemical modifications to bone mineral caused by storage protocols. In: 7th World Congress of Biomechanics (WCB 2014), Boston, 6 July 2014.
- Zioupos P, Cook R, Aspden RM & Coats AM (2008) Bone quality issues and matrix properties in OP cancellous bone. In: 2nd Conference on Applied Biomechanics: Medicine Meets Engineering, Regensburg, 13-15 June 2008.
- Zioupos P (2007) Material Property Changes in Osteoporotic Cancellous Bone. In: IMechE Seminar Material Properties for Finite Element Simulations, IMechE Headquarters, London.
- Peterlik H, Puchegger S, Rennhofer H, Loidl D, Stoll J, Zioupos P & Bernstorff S (2006) Relaxation of human bone at the nanoscale. In: Anniversary symposium: 10 years Austrian SAXS station at Elettra, SAXS on nanosystems - science and technology, Trieste, 23 November 2006.
- Zioupos P (2006) Determination of "age at death" by laboratory based analytical methods for forensic purposes using human bone". In: 5th World Congress of Biomechanics, Munich, Germany.
- Peterlik H, Puchegger S, Rennhofer H, Loidl D, Stoll J, Zioupos P & Bernstorff S (2006) Relaxation of human bone at the nanoscale. In: 2nd Viennese biomaterials symposium, Vienna, 22 November 2006.
- Cook RB, Zioupos P, Curwen C & Tasker T (2006) Cancellous fracture toughness and compressive properties at the head of the femur vs. peripheral quantitative ultrasound measurements. In: 1st European Symposium on Ultrasonic Characterization of Bone , Paris, France.
- Zioupos P, Cook R, Collins D & Tucker J (2006) The predictive ability of two quantitative Ultrasound Bone scanners in comparison to DXA. In: ESB 2004, Hertogenbosch, the Netherlands, 4-7 July 2006.
- Zioupos P (2005) Age related changes of bone's material properties. In: Harold M Frost Memorial Conference, Manchester Metropolitan University, 3 May 2005.
- Zioupos P, Christodoulou G, Giles R & Williams A (2005) A Laboratory method to determine 'age of death' for forensic purposes using human bone. In: Forensic Science and Investigation of Atrocity Crimes and Mass Fatalities, Inforce Foundation, Bournemouth University UK.
- Hardy R, Watson J, Frampton R, Page M, Zioupos P, Cook R, Kennedy A, Sproston P, Forrester B & Peach S BOSCOS - Development and benefits of a Bone Scanning system. In: 2005 International IRCOBI Conference on the Biomechanics of Impact, Prague, 21 September 2005.
- Zioupos P, Christodoulou G, Giles R & Williams A (2005) An Analytical Method to determine 'Age of Death' for Forensic Purposes using Human Bone. In: 17th Meeting of the International Association of Forensic Sciences, Hong Kong.
- Zioupos P, Blythe A & Tasker T (2004) Mechanical performance and reliability of two different methods of suturing semitendinosus grafts for ACL reconstructions. In: ESB 2004, Hertogenbosch, the Netherlands, 4-7 July 2004.
- Zioupos P, Gresle M & Winwood K (2004) Microstructural and physical characteristics effects on the fatigue strength of human cortical bone. In: ESB 2004, Hertogenbosch, the Netherlands, 4 July 2004.
- Zioupos P, Alba-Fernandez C & Casinos A (2004) Nanoindentation characterization of dolphin bones: a possible model for osteoporosis?. In: ESB 2004, Hertogenbosch, the Netherlands, 4 July 2004.
- Zioupos P (2004) In-vivo fatigue microcracks in human bone: material properties of the surrounding bone matrix. In: ESB 2004, Hertogenbosch, the Netherlands, 4 July 2004.
- Zioupos P & Currey JD (2004) Notch sensitivity of vertebrate mineralised tissues in impact: an adaptive reason for a lower limit of mineralisation?. In: ESB 2004, 4-7 July 2004, Hertogenbosch, The Netherlands, 4 July 2004.
- Zioupos P (2004) Assessment of bone matrix at sites of in-vivo fatigue microcracks by nanoindentation. In: 16th International Bone Densitometry workshop, Annecy, France, 20 June 2004.
- Zioupos P, Hardy R, Watson J & Cook R (2004) BOSCOS - Bone Scanning for Occupant Safety. In: Vehicle Safety 2004, One Birdcage Walk, London, 14 December 2004.
- Zioupos P, Cook RB & Collins D (2004) Comparison of Patient Screening Techniques for Dual-Energy X-Ray Absorptiometry (DXA). In: 10th Conference on Osteoporosis, Harrowgate UK, 28 November - 1 December 2004.
- Zioupos P & Winwood K (2004) Rates of Development of elastic and plastic strains during fatigue of human cortical bone in tension, compression and shear. In: ESB 2004, Hertogenbosch, the Netherlands, 4 July 2004.
- Zioupos P, Cotton JR, Winwood K & Taylor M (2003) Relationship between cycles to failure and rates of damage and creep in fatigue tests of human cortical bone. In: ASME 2003 Summer Bioengineering Conference, Sonesta Beach, Key Biscayne, Florida, USA, 25 June 2003.
- Zioupos P, Fernandez C & Casinos A (2003) Geometry and mechanics in dolphin bones. A possible model for osteoporosis. In: Experimental Biology, Ann. Main Meeting, Southampton, UK, 1 April 2003.
- Zioupos P, Blythe A & Tasker TPB (2003) Mechanical Performance of Two Different Methods of Suturing Semitendinosus Grafts for Anterior Cruciate Ligament Reconstruction. In: The British Association for Surgery of the Knee (BASK) annual meeting, Low Wood Hotel, Lake Windermere, 4-5 April 2003.
- Zioupos P, Cook R, Collins D & Curwen C (2003) Comparison of inter-site bone densitometry measurements and the short-term precision of two bone quantitative ultrasound scanners. In: IPEM Annual Scientific Meeting, 15-17 September 2003, University of Bath, Bath UK, 15 September 2003.
- Zioupos P, Blythe A & Tasker TPB (2003) Mechanical Performance of Two Different Methods of Suturing Semitendinosus Grafts for Anterior Cruciate Ligament Reconstruction. In: IPEM annual Scientific Meeting, Bath, 15-17 September 2003.
- Zioupos P, Cotton JR, Winwood K & Taylor M (2002) Nonlinear damage Theory applied to two-step fatigue failure prediction of bone.. In: 4th World Congress of Biomechanics, Calgary, Canada, 4 August 2002.
- Zioupos P, Casinos A & Winwood K (2002) In-plane shear strength and fatigue damage properties of laminar bone. In: 13th Eur. Soc. Biomech. Conf., Wroclaw, Poland, 1 September 2002.
- Zioupos P, Winwood K, Cotton J & Taylor M (2002) The development of elastic and 'plastic' strains during fatigue damage accumulation of human cortical bone. In: 13th Eur. Soc. Biomech. Conf., Wroclaw, Poland, 1 September 2002.
- Zioupos P, Aspden RM & Coats AM (2002) Material property issues in OP cancellous bone. In: 13th Eur. Soc. Biomech. Conf.,, Wroclaw, Poland, 1 September 2002.
- Zioupos P, Cotton JR, Winwood K & Taylor M (2002) Creep formulation of strain accumulation during tensile fatigue of cortical bone. In: 4th World Congress of Biomechanics, Calgary, Canada, 4 August 2002.
- Zioupos P, Cotton JR & Taylor M (2001) Simulation of Material Property Evolution of Cortical Bone in Fatigue Bending and its Implications on Cancellous Bone. In: XVIII Congress of the International Society of Biomechanics, Zurich, Switzerland, 8 July 2001.
- Zioupos P, Winwood K & Wise V (2001) Material property changes in bovine bone following various physicochemical treatments. In: XVIII Congress of the International Society of Biomechanics, Zurich, Switzerland, 8 July 2001.
- Zioupos P, Taylor M & Cotton J (2001) A Stochastic approach to simulate the variable fatigue life of cortical bone using combined CDM and FE method. In: 16th Eur. Conf. of Eur. Soc. Biomaterials, London, UK, 12 September 2001.
- Zioupos P, Winwood K, Cotton JR & Taylor M (2001) The development of 'plastic' and elastic strains in fatigue of femoral cortical bone: a possible contributor to implant failure.. In: Biological Mechanics Network 2001, Oswestry, UK, 15 November 2001.
- Zioupos P, Cotton J, Winwood K, Anderson P & Taylor M (2001) Static FEA of cortical bone tensile test samples with variations in modulus identified from micro-CT scans.. In: 16th Eur. Conf. of Eur. Soc. Biomaterials, London, UK, 12 September 2001.
- Zioupos P, Winwood K, Rogers KD & Wise V (2001) Mechanical and Material property changes in bovine cortical bone subject to various physicochemical treatments. In: 16th Eur. Conf. of Eur. Soc. Biomaterials, London, UK, 12 September 2001.
- Zioupos P, Aspden RM, Rogers KD, Noriega E & Wise V (2001) Material quality aspects of osteoporotic cancellous bone. In: XVIII Congress of the International Society of Biomechanics, Zurich, Switzerland, 8 July 2001.
- Zioupos P, Winwood K, Cotton J & Taylor M (2001) The development of 'plastic' strains during fatigue damage accumulation. In: XVIII Congress of the International Society of Biomechanics, Zurich, Switzerland, 8 July 2001.
- Zioupos P, Winwood K, Cotton J & Taylor M (2001) Measurements of 'plastic and elastic strains during tension or compression fatigue of ageing human cortical bone.. In: 16th Eur. Conf. of Eur. Soc. Biomaterials, London, UK, 12 September 2001.
- Barbenel JC, Zioupos P & Fisher J (1986) The mechanical properties of bovine pericardium. In: Heart valve engineering, London, 4 December 1986.
- Zioupos P, Alba-Fernandez C & Casinos A Ontogenetic scaling of cross-sectional parameters in striped dolphin and Franciscana dolphin radius. In: International Congress of Vertebrate Morphology, Jena, Germany.
- Zioupos P, Hansen U & Currey J The development of microdamage as a function of strain rate in human cortical bone. In: 5th World Congress of Biomechanics, Munich, Germany.
- Zioupos P, Cotton JR & Taylor M Simulated Material property degradation during Fatigue of human Cancellous bone, as modelled by a regular Honeycomb Structure. In: ASME 2001 Summer Bioengineering Conference, Snowbird, UT, 27 June - 1 July 2001.
- Sedman A, Currey J & Zioupos P The fracture process in mineralised tissues visualised by whitening, an indicator of microdamage. In: 5th World Congress of Biomechanics, Munich, Germany.
- Cook RB, Zioupos P, Curwen C & Tasker T Using peripheral qualitative ultrasound to predict Fracture Mechanics and compressive. In: 5th World Congress of Biomechanics, Munich, Germany.
- Zioupos P & Rogers KD Examining Tooth - a bone like tissue - by nanoindentation and micro-XRD in a complementary mode. In: CAMTEC Workshop, Dept of Materials Science and Metallurgy, of University of Cambridge.
Books
- Zioupos P, Watson J, Hardy RN, Frampton O, Williams P, Cook AJ, Kennedy P, Sproston P, Forrester S & Peach S (2004) BOSCOS Bone Scanning for Occupant Safety. In: Special Issue of Vehicle Safety 2004, Inst. Mech. Eng. Conference, London 2004.
- Zioupos P, Currey JD & Rho JY (2004) Bones: the need for intrinsic material and architectural design. In: Optimisation Mechanics in Nature, Design & Nature Series, WIT Press 2004, p. 93-117.