Contact Dr Iva Chianella
- Tel: +44 (0) 1234 758322
- Email: i.chianella.1998@cranfield.ac.uk
- ORCID
Areas of expertise
- Biosensors & Diagnostics
- Nanomaterials
- Smart Materials
Background
Dr Iva Chianella is an experienced Scientist with a strong research track record on the development of affinity sensors/biosensors based on natural and artificial receptors for clinical, environmental, food, safety and industrial applications.
After receiving her first degree in Chemistry from the University of Florence, and her PhD in Bioscience from Cranfield University, Dr Chianella was appointed to Lecturer in 2007 and to Senior Lecturer in 2020. She has around 55 peer reviewed papers, 7 book chapters and 4 patent in the area of diagnostics and on novel polymeric materials and their use in several analytical systems. Dr Chianella main research interests are: i) on the development of chemical and biochemical sensors/nano-sensors for point-of-care and in-field applications; ii) on the synthesis of novel polymeric nanomaterials (e.g. Molecularly Imprinted Polymers Nanoparticles) for sensors and assays.
Current activities
Dr Chianella is currently active both in research and teaching. Her main research interests include:
Chemical and biochemical sensors/nanosensors (electrochemical, piezoelectric and optical) for medical, environmental and industrial applications;
Synthesis of novel receptors for sensors and assay development;
Molecularly imprinted polymers and molecularly imprinted polymer nanoparticles;
Nanomaterials such as iron oxide nanoparticles for biomedical applications.
Clients
During her academic career, Dr Chianella has had the opportunity to collaborate with several industrial clients (e.g. GSK, DSM, Philips, Sphere Medical, Infigo Diagnostics, MIP Diagnostics, CEAD) and have her research funded by several Research Councils (e.g. Innovate UK, DSTL, EPSRC) and EU funding bodies.
Publications
Articles In Journals
- Demirhan A, Chianella I, Patil SB & Khalid A. (2024). A low-cost miniature immunosensor for haemoglobin as a device for the future detection of gastrointestinal bleeding. The Analyst, 149(4)
- Mishra RK, Verma K, Chianella I, Goel S & Nezhad HY. (2024). Nanomaterial integration in micro LED technology: Enhancing efficiency and applications. Next Nanotechnology, 5
- Wignarajah S, Chianella I & Tothill IE. (2023). Development of Electrochemical Immunosensors for HER-1 and HER-2 Analysis in Serum for Breast Cancer Patients. Biosensors, 13(3)
- Taylor JA, Fourie T, Powell M & Chianella I. (2023). Evidence for some antimicrobial properties of English churchyard lichens. Access Microbiology, 5(6)
- Mishra RK, Li D, Chianella I, Goel S, Lotfian S, .... (2023). Low electric field induction in BaTiO3-epoxy nanocomposites. Functional Composite Materials, 4(1)
- Mishra RK, Goel S, Chianella I & Yazdani Nezhad H. (2023). Graphene Nanoplatelets/Barium Titanate Polymer Nanocomposite Fibril: A Remanufactured Multifunctional Material with Unprecedented Electrical, Thermomechanical, and Electromagnetic Properties (Adv. Sustainable Syst. 11/2023). Advanced Sustainable Systems, 7(11)
- Mishra RK, Goel S, Chianella I & Yazdani Nezhad H. (2023). Graphene Nanoplatelets/Barium Titanate Polymer Nanocomposite Fibril: A Remanufactured Multifunctional Material with Unprecedented Electrical, Thermomechanical, and Electromagnetic Properties. Advanced Sustainable Systems, 7(11)
- Gurung S, Gucci F, Cairns G, Chianella I & Leighton GJT. (2022). Hollow Silica Nano and Micro Spheres with Polystyrene Templating: A Mini-Review. Materials, 15(23)
- Hemben A, Chianella I & Leighton GJT. (2021). Surface Engineered Iron Oxide Nanoparticles Generated by Inert Gas Condensation for Biomedical Applications. Bioengineering, 8(3)
- Odiegwu C.N.C. , Chianella I. , Azubike N.C. , Odiegwu U.O . & Ogbuowelu O.S. . (2021). Liver Function Tests Values in Albino Wistar Rats Administered with Isolated Nigeria Achatina achatina Snail Lectin.. GSC Biological and Pharmaceutical Sciences, 15(02)
- Wei W, Thakur VK, Li S & Chianella I. (2021). Self-switchable polymer reactor with PNIPAM-PAm smart switch capable of tandem/simple catalysis. Polymer, 235(November)
- D’Aurelio R, Tothill IE, Salbini M, Calò F, Mazzotta E, .... (2021). A Comparison of EIS and QCM NanoMIP-Based Sensors for Morphine. Nanomaterials, 11(12)
- Gedara AKA, Chianella I, Bhattacharyya D, Endrino JL & Zhang Q. (2021). Alkali-treated wheat gluten cross-linked with sodium alginate as a bio-based wood adhesive for interior grade particleboard. BioResources, 16(4)
- Gedara AKA, Chianella I, Endrino JL & Zhang Q. (2021). Adhesiveless bonding of wood – A review with a focus on wood welding. BioResources, 16(3)
- Wei W, Xiao P, Thakur VK, Chianella I & Li S. (2020). Smart bilayer polymer reactor with cascade/non-cascade switching catalyst characteristics. Materials Today Chemistry, 17
- D’Aurelio R, Chianella I, Goode JA & Tothill IE. (2020). Molecularly Imprinted Nanoparticles Based Sensor for Cocaine Detection. Biosensors, 10(3)
- Turner NW, Bloxham M, Piletsky SA, Whitcombe MJ & Chianella I. (2017). The use of a quartz crystal microbalance as an analytical tool to monitor particle/surface and particle/particle interactions under dry ambient and pressurized conditions: a study using common inhaler components. The Analyst, 142(1)
- Altintas Z, Chianella I, Ponte GD, Paulussen S, Gaeta S, .... (2016). Development of functionalized nanostructured polymeric membranes for water purification. Chemical Engineering Journal, 300
- Cáceres C, Canfarotta F, Chianella I, Pereira E, Moczko E, .... (2016). Does size matter? Study of performance of pseudo-ELISAs based on molecularly imprinted polymer nanoparticles prepared for analytes of different sizes. The Analyst, 141(4)
- Mazzotta E, Turco A, Chianella I, Guerreiro A, Piletsky SA, .... (2016). Solid-phase synthesis of electroactive nanoparticles of molecularly imprinted polymers. A novel platform for indirect electrochemical sensing applications. Sensors and Actuators B: Chemical, 229
- Rodríguez-Dorado R, Carro AM, Chianella I, Karim K, Concheiro A, .... (2016). Oxytetracycline recovery from aqueous media using computationally designed molecularly imprinted polymers. Analytical and Bioanalytical Chemistry, 408(24)
- Karim K, Giannoudi L, Piletska E, Chianella I, Henry OYF, .... (2015). Development of MIP sensor for monitoring propofol in clinical procedures. Journal of the Chinese Advanced Materials Society, 3(3)
- Cavaleiro PhD E, Duarte PhD AS, Esteves PhD AC, Correia PhD A, WhitcombePhD MJ, .... (2015). Novel Linear Polymers Able to Inhibit Bacterial Quorum Sensing. Macromolecular Bioscience, 15(5)
- Korposh S, Chianella I, Guerreiro A, Caygill S, Piletsky S, .... (2014). Selective vancomycin detection using optical fibre long period gratings functionalised with molecularly imprinted polymer nanoparticles. The Analyst, 139(9)
- Shutov RV, Guerreiro A, Moczko E, de Vargas‐Sansalvador IP, Chianella I, .... (2014). Introducing MINA – The Molecularly Imprinted Nanoparticle Assay. Small, 10(6)
- Piletska EV, Chianella I, Turner APF, Takayama K, Thaveeprungsriporn V, .... (2014). Optical biosensors based on universal pH indicator as a reporter for quantification of clinically relevant compounds. Journal of the Chinese Advanced Materials Society, 2(2)
- Chianella I, Guerreiro A, Moczko E, Caygill JS, Piletska EV, .... (2013). Direct Replacement of Antibodies with Molecularly Imprinted Polymer Nanoparticles in ELISA—Development of a Novel Assay for Vancomycin. Analytical Chemistry, 85(17)
- Singh KP, Choudhary MK, Chianella I & Singh P. (2013). Development of Non-Labeled QCM Biosensor for the Detection of <i>β</i>-Galactosidase: A Comparative Study of Gold and Polystyrene Nanoparticles. Advances in Nanoparticles, 02(02)
- Kyprianou D, Chianella I, Guerreiro A, Piletska EV & Piletsky SA. (2013). Development of optical immunosensors for detection of proteins in serum. Talanta, 103
- Piletska EV, Piletsky SS, Whitcombe MJ, Chianella I & Piletsky SA. (2012). Development of a New Microtiter Plate Format for Clinically Relevant Assays. Analytical Chemistry, 84(4)
- Malitesta C, Mazzotta E, Picca RA, Poma A, Chianella I, .... (2012). MIP sensors – the electrochemical approach. Analytical and Bioanalytical Chemistry, 402(5)
- Akbulut M, Lakshmi D, Whitcombe MJ, Piletska EV, Chianella I, .... (2011). Microplates with Adaptive Surfaces. ACS Combinatorial Science, 13(6)
- Whitcombe MJ, Chianella I, Larcombe L, Piletsky SA, Noble J, .... (2011). The rational development of molecularly imprinted polymer-based sensors for protein detection. Chem. Soc. Rev., 40(3)
- Whitcombe MJ, Chianella I, Larcombe L, Piletsky SA, Noble J, .... (2011). ChemInform Abstract: The Rational Development of Molecularly Imprinted Polymer‐Based Sensors for Protein Detection. ChemInform, 42(23)
- Piletska EV, Stavroulakis G, Karim K, Whitcombe MJ, Chianella I, .... (2010). Attenuation of Vibrio fischeri Quorum Sensing Using Rationally Designed Polymers. Biomacromolecules, 11(4)
- Kyprianou D, Guerreiro AR, Nirschl M, Chianella I, Subrahmanyam S, .... (2010). The application of polythiol molecules for protein immobilisation on sensor surfaces. Biosensors and Bioelectronics, 25(5)
- Berti F, Todros S, Lakshmi D, Whitcombe MJ, Chianella I, .... (2010). Quasi-monodimensional polyaniline nanostructures for enhanced molecularly imprinted polymer-based sensing. Biosensors and Bioelectronics, 26(2)
- Bossi A, Whitcombe MJ, Uludag Y, Fowler S, Chianella I, .... (2010). Synthesis of controlled polymeric cross-linked coatings via iniferter polymerisation in the presence of tetraethyl thiuram disulphide chain terminator. Biosensors and Bioelectronics, 25(9)
- Yañez F, Chianella I, Piletsky SA, Concheiro A & Alvarez-Lorenzo C. (2010). Computational modeling and molecular imprinting for the development of acrylic polymers with high affinity for bile salts. Analytica Chimica Acta, 659(1-2)
- McColl J, Horvath R, Aref A, Larcombe L, Chianella I, .... (2009). Polyphenol Control of Cell Spreading on Glycoprotein Substrata. Journal of Biomaterials Science, Polymer Edition, 20(5-6)
- Romero Guerra M, Chianella I, Piletska EV, Karim K, Turner APF, .... (2009). Development of a piezoelectric sensor for the detection of methamphetamine. The Analyst, 134(8)
- Lakshmi D, Bossi A, Whitcombe MJ, Chianella I, Fowler SA, .... (2009). Electrochemical Sensor for Catechol and Dopamine Based on a Catalytic Molecularly Imprinted Polymer-Conducting Polymer Hybrid Recognition Element. Analytical Chemistry, 81(9)
- Lakshmi D, Whitcombe MJ, Davis F, Chianella I, Piletska EV, .... (2009). Chimeric polymers formed from a monomer capable of free radical, oxidative and electrochemical polymerisation. Chemical Communications, 0(19)
- Garcinuño RM, Chianella I, Guerreiro A, Mijangos I, Piletska EV, .... (2009). The stabilisation of receptor structure in low cross-linked MIPs by an immobilised template. Soft Matter, 5(2)
- Guerreiro AR, Chianella I, Piletska E, Whitcombe MJ & Piletsky SA. (2009). Selection of imprinted nanoparticles by affinity chromatography. Biosensors and Bioelectronics, 24(8)
- Mijangos I, Guerreiro A, Piletska E, Whitcombe MJ, Karim K, .... (2009). Macroradical initiated polymerisation of acrylic and methacrylic monomers. Journal of Separation Science, 32(19)
- Piletska EV, Guerreiro AR, Romero-Guerra M, Chianella I, Turner APF, .... (2008). Design of molecular imprinted polymers compatible with aqueous environment. Analytica Chimica Acta, 607(1)
- Pascale M, De Girolamo A, Visconti A, Magan N, Chianella I, .... (2008). Use of itaconic acid-based polymers for solid-phase extraction of deoxynivalenol and application to pasta analysis. Analytica Chimica Acta, 609(2)
- Piletska EV, Villoslada FN, Chianella I, Bossi A, Karim K, .... (2008). Extraction of domoic acid from seawater and urine using a resin based on 2-(trifluoromethyl)acrylic acid. Analytica Chimica Acta, 610(1)
- Chianella I, Karim K, Piletska EV, Preston C & Piletsky SA. (2006). Computational design and synthesis of molecularly imprinted polymers with high binding capacity for pharmaceutical applications-model case: Adsorbent for abacavir. Analytica Chimica Acta, 559(1)
- Piletsky SA, Mijangos I, Guerreiro A, Piletska EV, Chianella I, .... (2005). Polymer Cookery: Influence of Polymerization Time and Different Initiation Conditions on Performance of Molecularly Imprinted Polymers. Macromolecules, 38(4)
- KARIM K, BRETON F, ROUILLON R, PILETSKA E, GUERREIRO A, .... (2005). How to find effective functional monomers for effective molecularly imprinted polymers?. Advanced Drug Delivery Reviews, 57(12)
- Piletsky SA, Guerreiro A, Piletska EV, Chianella I, Karim K, .... (2004). Polymer Cookery. 2. Influence of Polymerization Pressure and Polymer Swelling on the Performance of Molecularly Imprinted Polymers. Macromolecules, 37(13)
- Chianella I, Piletsky SA, Tothill IE, Chen B & Turner APF. (2003). MIP-based solid phase extraction cartridges combined with MIP-based sensors for the detection of microcystin-LR. Biosensors and Bioelectronics, 18(2-3)
- Chianella I, Lotierzo M, Piletsky SA, Tothill IE, Chen B, .... (2002). Rational Design of a Polymer Specific for Microcystin-LR Using a Computational Approach. Analytical Chemistry, 74(6)
- Marrazza G, Chianella I & Mascini M. (1999). Disposable DNA electrochemical sensor for hybridization detection1This paper was presented at the Fifth World Congress on Biosensors, Berlin, Germany, 3–5 June 1998.1. Biosensors and Bioelectronics, 14(1)
- Marrazza G, Chianella I & Mascini M. (1999). Disposable DNA electrochemical biosensors for environmental monitoring. Analytica Chimica Acta, 387(3)
- Odiegwu C.N.C. , Chianella I. , Odiegwu U.O. , Okolie U.V. & Ifejirika E.C. . Leucocytes, urea and glucose levels in Albino Wistar rats exposed to doses of isolated Achatina achatina snail lectin. World Journal of Biology Pharmacy and Health Sciences, 6(3)
- A B, I C, K C & M Z. Development of Solid-Phase Extraction Using Molecularly Imprinted Polymer for the Analysis of Organophosphorus Pesticides-(Chlorpyrifos) in Aqueous Solution. Journal of Chromatography & Separation Techniques, 07(06)
Conference Papers
- Des Azevedo S, Lakshmi D, Chianella I, Whitcombe MJ, Karim K, .... (2013). Molecularly Imprinted Polymer-Hybrid Electrochemical Sensor for the Detection of β-Estradiol
- Cavaleiro E, Chianella I, Whitcombe MJ, Piletsky SA, Correia A, .... (2011). Synthetic polymers capable of suppressing virulence of bacterial fish pathogens
- Lakshmi D, Chianella I, Whitcombe MJ, Piletska EV, Karim K, .... (2010). Synthesis and Characterization of Novel Conducting Monomer Showing Chimeric Polymerisation Behaviour: Versatile Applications in Defence and Aerospace Research
- Berti F, Todros S, Marrazza G, Faglia G, Lakshmi D, .... (2010). Polyaniline nanostructures for enhanced molecularly imprinted polymer-based sensing
- Todros S, Francesca Berti F, Faglia G, Marrazza G, Lakshmi D, .... (2010). Conductive polymer nanotubes for biochemical gas sensing
- Berti F, Todros S, Marrazza G, Faglia G, Piletsky SA, .... (2009). Template synthesis of polyaniline nanostructures for sensing applications
- Berti F, Todros S, Marrazza G, Faglia G, Piletsky SA, .... (2009). Conductive polyaniline (PANI) nanostructures for sensing applications
- Kyprianou D, Guerreiro AR, Chianella I, Piletska EV, Fowler SA, .... (2009). New reactive polymer for protein immobilisation on sensor surfaces
- Breton F, Rouillon R, Piletska EV, Karim K, Guerreiro A, .... (2007). Virtual imprinting as a tool to design efficient MIPs for photosynthesis-inhibiting herbicides
- Mijangos I, Navarro-Villoslada F, Guerreiro A, Piletska E, Chianella I, .... (2006). Influence of initiator and different polymerisation conditions on performance of molecularly imprinted polymers
- Piletska EV, Romero-Guerra M, Chianella I, Karim K, Turner APF, .... (2005). Towards the development of multisensor for drugs of abuse based on molecular imprinted polymers
Books
- Chianella I. (2023). QCM Strategies for Fundamental and Applied Measurements on Particles and Formulations In Piezoelectric Sensors (18). Springer International Publishing.
- Giuliani A, Chianella I & Gumina S. (2017). The Impact of Nanomedicine on Rotator Cuff Lesions: A Future Outlook In Rotator Cuff Tear. Springer International Publishing.
- Piletsky SA, Chianella I & Whitcombe MJ. (2013). Molecularly Imprinted Polymers In Encyclopedia of Biophysics. Springer Berlin Heidelberg.
- Chianella I, Karras K, Lakshmi D, Whitcombe MJ & Marson S. (2012). Conductive Polymers for Plastic Electronics In Li SJ, Ge Y, Piletsky SA & Lunec J (eds), Molecularly Imprinted Sensors. Elsevier.
- Piletsky S, Piletsky S & Chianella I. (2012). Chapter 14 MIP-based Sensors In Molecularly Imprinted Sensors. Elsevier.
- Chianella I, Karras K, Lakshmi D, Whitcombe MJ & Marson S. (2012). Chapter 12 Conductive Polymers for Plastic Electronics In Molecularly Imprinted Sensors. Elsevier.
- Chianella I, Karras K, Lakshmi D, Whitcombe MJ & Marson S. (2012). Conductive Polymers for Plastic Electronics In Molecularly Imprinted Sensors.
- Piletsky S, Piletsky S & Chianella I. (2012). MIP-based Sensors In Molecularly Imprinted Sensors.
- Piletsky S, Piletsky S & Chianella I. (2012). MIP-based Sensors In Molecularly Imprinted Sensors. Elsevier.
- Berti F, Marrazza G, Mascini M, Todros S, Baratto C, .... (2011). One-Dimensional Polyaniline Nanotubes for Enhanced Chemical and Biochemical Sensing In Neri G, Donato N, d'Amico A & Di Natale C (eds), Lecture Notes in Electrical Engineering (91 LNEE). Springer Netherlands.
- Nicholls IA, Piletsky SA, Chen B, Chianella I & Turner APF. (2005). Terhodynamic considerations and the use of molecular modelling as a tool for predicting MIP performance In Molecularly imprinted materials: Science and technology. Marcel Dekker.
- Chen B, Nicholls I, Turner A, Piletsky S & Chianella I. (2004). Thermodynamic Considerations and the Use of Molecular Modeling as a Tool for Predicting MIP Performance In Molecularly Imprinted Materials. CRC Press.
- Nicholls IA, Piletsky SA, Chen B, Chianella I & Turner APF. (2004). Molecularly Imprinted Materials In Yan M(ed.), Molecularly Imprinted Materials: Science and Technology. CRC Press.
