Contact Dr Chris Walton
- Tel: +44 (0) 1234 752974
- Email: c.walton@cranfield.ac.uk
- ORCID
Areas of expertise
- Air
- Biomedical Engineering
- Biosensors & Diagnostics
- Environment and Health
- Instrumentation, Sensors and Measurement Science
- Natural Capital
- Water Science and Engineering
Background
BSc Biological Sciences, University of Leicester
MSc Biological Computation, University of York
PhD Bioengineering (cardiac pacemakers), CNAA
MSc Medical Diagnostics, Cranfield University.
Dr Chris Walton's research career has spanned three decades and an eclectic mix of disciplines including engineering, software development, mathematical modelling, database design, metabolic medicine and statistics.
Chris is a Member of the Institute of Biology, a Chartered Biologist, and an Affiliate of the Royal Society of Chemistry.
Current activities
Trace gas analysis
Development of novel diagnostics for medicine and environmental health
Air quality monitoring
Sensor networks for environmental analysis
Clients
EPSRC
NERC
Department for Transport
Wellcome Trust
Innovate UK
Thales UK
Johnson Matthey
Nutriad Ltd
Consultancy and air quality monitoring for SMEs and other organisations.
Publications
Articles In Journals
- Anigilaje EA, Nasir ZA & Walton C. (2024). Exposure to benzene, toluene, ethylbenzene, and xylene (BTEX) at Nigeria's petrol stations: a review of current status, challenges and future directions. Frontiers in Public Health, 12
- Lourenço C, Campo P, Walton C, Alamar MC & Coulon F. (2021). Overview of Field-Based Analytical Techniques, Devices and Kits to Determine Petroleum Hydrocarbons in Soil. CONCAWE Reports, 21(3)
- Lourenço C, Bergin S, Hodgkinson J, Francis D, Staines SE, .... (2020). Instrumentation for quantitative analysis of volatile compounds emission at elevated temperatures. Part 1: Design and implementation. Scientific Reports, 10(1)
- Lourenço C, Francis D, Fowler DP, Staines SE, Hodgkinson J, .... (2020). Instrumentation for quantitative analysis of volatile compounds emission at elevated temperatures. Part 2: Analysis of carbon fibre reinforced epoxy composite. Scientific Reports, 10(1)
- Patel M, Fowler D, Sizer J & Walton C. (2019). Faecal volatile biomarkers of Clostridium difficile infection. PLOS ONE, 14(4)
- Mercer E, Davey CJ, Campo P, Fowler D, Williams L, .... (2019). Quantification of liquid phase faecal odourants to evaluate membrane technology for wastewater reuse from decentralised sanitation facilities. Environmental Science: Water Research & Technology, 5(1)
- Walton C, Montoya MPB, Fowler DP, Turner C, Jia W, .... (2016). Enteral feeding reduces metabolic activity of the intestinal microbiome in Crohn’s disease: an observational study. European Journal of Clinical Nutrition, 70(9)
- Hopes K, Cauchi M, Walton C, MacQueen H, Wassif W, .... (2015). A novel method for the analysis of clinical biomarkers to investigate the effect of diet on health in a rat model. The Analyst, 140(9)
- Cauchi M, Fowler DP, Walton C, Turner C, Waring RH, .... (2015). Comparison of GC-MS, HPLC-MS and SIFT-MS in conjunction with multivariate classification for the diagnosis of Crohn's disease in urine. Analytical Methods, 7(19)
- Walton C, Patel M, Pitts D, Knight P, Hoashi S, .... (2014). The use of a portable breath analysis device in monitoring type 1 diabetes patients in a hypoglycaemic clamp: validation with SIFT-MS data. Journal of Breath Research, 8(3)
- Cauchi M, Fowler DP, Walton C, Turner C, Jia W, .... (2014). Application of gas chromatography mass spectrometry (GC–MS) in conjunction with multivariate classification for the diagnosis of gastrointestinal diseases. Metabolomics, 10(6)
- Walton C, Fowler DP, Turner C, Jia W, Whitehead RN, .... (2013). Analysis of Volatile Organic Compounds of Bacterial Origin in Chronic Gastrointestinal Diseases. Inflammatory Bowel Diseases, 19(10)
- Jia W, Whitehead RN, Griffiths L, Dawson C, Bai H, .... (2012). Diversity and distribution of sulphate-reducing bacteria in human faeces from healthy subjects and patients with inflammatory bowel disease. FEMS Immunology & Medical Microbiology, 65(1)
- Turner C, Walton C, Hoashi S & Evans M. (2009). Breath acetone concentration decreases with blood glucose concentration in type I diabetes mellitus patients during hypoglycaemic clamps. Journal of Breath Research, 3(4)
- Coulon F, Orsi R, Turner C, Walton C, Daly P, .... (2009). Understanding the fate and transport of petroleum hydrocarbons from coal tar within gasholders. Environment International, 35(2)
- Turner C, Parekh B, Walton C, Španěl P, Smith D, .... (2008). An exploratory comparative study of volatile compounds in exhaled breath and emitted by skin using selected ion flow tube mass spectrometry. Rapid Communications in Mass Spectrometry, 22(4)
- Godsland IF, Bruce R, Jeffs JAR, Leyva F, Walton C, .... (2004). Inflammation markers and erythrocyte sedimentation rate but not metabolic syndrome factor score predict coronary heart disease in high socioeconomic class males: the HDDRISC study. International Journal of Cardiology, 97(3)
- Godsland IF & Walton C. (2001). Maximizing the success rate of minimal model insulin sensitivity measurement in humans: The importance of basal glucose levels. Clinical Science, 101(1)
- Leyva F, Godsland IF, Villar J, Espino Montoro A, Nuñez A, .... (1999). Insulin sensitivity is modulated by the I/D ACE gene polymorphism, but not by the TRP64ARG β
3 -adrenoceptor gene polymorphism, the M235T angiotensinogen gene polymorphism or the ε2/ε3/ε4 apolipoprotein E gene polymorphism. Heart, 81(SUPPL. 1) - Wingrove CS, Walton C & Stevenson JC. (1998). The effect of menopause on serum uric acid levels in non-obese healthy women. Metabolism, 47(4)
- Godsland , Leyva , Walton , Worthington & Stevenson . (1998). Associations of smoking, alcohol and physical activity with risk factors for coronary heart disease and diabetes in the first follow‐up cohort of the Heart Disease and Diabetes Risk Indicators in a Screened Cohort study (HDDRISC‐1). Journal of Internal Medicine, 244(1)
- Leyva F, Godsland IF, Worthington M, Walton C & Stevenson JC. (1998). Factors of the Metabolic Syndrome. Arteriosclerosis, Thrombosis, and Vascular Biology, 18(2)
- Leyva F, Godsland IF, Ghatei M, Proudler AJ, Aldis S, .... (1998). Hyperleptinemia as a Component of a Metabolic Syndrome of Cardiovascular Risk. Arteriosclerosis, Thrombosis, and Vascular Biology, 18(6)
- Leyva F, Godsland IF, Proudler AJ, Gathei M, Walton C, .... (1998). Hyperleptinaemia: A new component of the metabolic syndrome of cardiovascular risk. Heart, 79(SUPPL. 1)
- Leyva F, Godsland IF, Worthington M, Walton C & Stevenson JC. (1998). Erratum: Factors of the metabolic syndrome: Baseline interrelationships in the first follow-up cohort of the HDDRISC-1 study (HDDRISC-1) (Arteriosclerosis, Thrombosis and Vascular Biology (1998) 18 (208-214)). Arteriosclerosis, Thrombosis, and Vascular Biology, 18(7)
- Godsland IF, Leyva F, Walton C, Worthington M & Stevenson JC. (1998). Associations of smoking, alcohol and physical activity with risk factors for coronary heart disease and diabetes risk in the first follow‐up cohort of the Heart Disease and Diabetes Risk Indicators in a Screened Cohort study (HDDRISC‐1). Journal of Internal Medicine, 243(7)
- Swan JW, Anker SD, Walton C, Godsland IF, Clark AL, .... (1997). Insulin Resistance in Chronic Heart Failure: Relation to Severity and Etiology of Heart Failure. Journal of the American College of Cardiology, 30(2)
- Lees B, Garland SW, Walton C & Stevenson JC. (1997). Evaluation of the European spine phantom in a multi-centre clinical trial. Osteoporosis International, 7(6)
- Godsland IF, Bruce R, Walton C, Leyva F, Worthington M, .... (1997). Insulin, HDL and coronary heart disease: 11.3 year evaluation of the first follow-up Cohort of the RISC study (RISC-1). Heart, 77(SUPPL. 1)
- Walton C, Lees B & Stevenson JC. (1996). Measuring body fat. The American Journal of Medicine, 101(2)
- Lees B, Garland SW, Walton C, Ross D, Whitehead MI, .... (1996). Role of oral pamidronate in preventing bone loss in postmenopausal women. Osteoporosis International, 6(6)
- Lees B, Garland SW, Walton C & Stevenson JC. (1996). Evaluation of the european spine phantom in a multicentre clinical trial. Osteoporosis International, 6(S1)
- Walton C, Lees B, Crook D, Worthington M, Godsland IF, .... (1995). Body fat distribution, rather than overall adiposity, influences serum lipids and lipoproteins in healthy men independently of age. The American Journal of Medicine, 99(5)
- Walton C. (1995). Relationships between insulin metabolism, serum lipid profile, body fat distribution and blood pressure in healthy men. Atherosclerosis, 118(1)
- Lees B, Molleson T, Arnett TR, Walton C & Stevenson JC. (1995). Gender differences in bone loss over two centuries. Bone, 17(3)
- Walton C, Lees B, Felton CV, Proudler AJ, Godsland IF, .... (1995). Relationship of ageing, total body and regional fat masses to insulin sensitivity, secretion and elimination in healthy men. Atherosclerosis, 115
- Bruce R, Godsland I, Walton C, Crook D & Wynn V. (1994). Associations between insulin sensitivity, and free fatty acid and triglyceride metabolism independent of uncomplicated obesity. Metabolism, 43(10)
- Swan JW, Walton C & Godsland IF. (1994). Assessment of Insulin Sensitivity in Man: A Comparison of Minimal Model- and Euglycaemic Clamp-Derived Measures in Health and Heart Failure. Clinical Science, 86(3)
- SWAN JW, WALTON C, GODSLAND IF, CLARK AL, COATS AJS, .... (1994). Insulin resistance in chronic heart failure. European Heart Journal, 15(11)
- Swan JW, Walton C, Godsland IF, Crook D, Oliver MF, .... (1994). Insulin resistance syndrome as a feature of cardiological syndrome X in non-obese men.. Heart, 71(1)
- Ley CJ, Swan J, Godsland IF, Walton C, Crook D, .... (1994). Insuline resistance, lipoproteins, body fat and hemostasis in nonobese men with angina and a normal or abnormal coronary angiogram. Journal of the American College of Cardiology, 23(2)
- Swan JW, Walton C, Godsland IF & Oliver MF. (1994). Assessment of Insulin Sensitivity in Man: A Comparison of Minimal Model and Euglycaemic Clamp Derived Measures in Health and Heart Failure. Clinical Science, 86(s30)
- Godsland IF, Gangar K, Walton C, Cust MP, Whitehead MI, .... (1993). Insulin resistance, secretion, and elimination in postmenopausal women receiving oral or transdermal hormone replacement therapy. Metabolism, 42(7)
- WALTON C, GODSLAND IF, PROUDLER AJ, WYNN V & STEVENSON JC. (1993). The effects of the menopause on insulin sensitivity, secretion and elimination in non‐obese, healthy women. European Journal of Clinical Investigation, 23(8)
- Godsland I, Walton C, Wynn V, Kumar S, Boulton A, .... (1992). Role of glucose and insulin resistance in development of type 2 diabetes mellitus. The Lancet, 340(8831)
- Walton C, Godsland IF, Proudler AJ, Felton CV & Wynn V. (1992). An apparently anomalous relationship between insulin and C-peptide concentrations in their initial response to intravenous glucose. Metabolism, 41(11)
- Godsland I & Walton C. (1992). Insulin resistance and cigarette smoking. The Lancet, 340(8819)
- Walton C, Godsland IF, Proudler AJ, Felton CV & Wynn V. (1992). Effect of body mass index and fat distribution on insulin sensitivity, secretion, and clearance in nonobese healthy men. Journal of Clinical Endocrinology and Metabolism, 75(1)
- Godsland IF, Wynn V, Walton C & Stevenson JC. (1992). Insulin resistance and cigarette smoking. The Lancet, 339(8809)
- Godsland IF, Walton C, Felton C, Proudler A, Patel A, .... (1992). Insulin resistance, secretion, and metabolism in users of oral contraceptives.. The Journal of Clinical Endocrinology & Metabolism, 74(1)
- Walton C, Godsland IF, Proudler AJ, Felton C & Wynn V. (1992). Evaluation of four mathematical models of glucose and insulin dynamics with analysis of effects of age and obesity. American Journal of Physiology-Endocrinology and Metabolism, 262(5)
- Godsland IF & Walton C. (1992). Minimal Models and the Labelled IVGTT. Diabetic Medicine, 9(5)
- Godsland IF, Crook D, Walton C, Wynn V & Oliver MF. (1992). Influence of insulin resistance, secretion, and clearance on serum cholesterol, triglycerides, lipoprotein cholesterol, and blood pressure in healthy men.. Arteriosclerosis and Thrombosis: A Journal of Vascular Biology, 12(9)
- Sidhu M, Crook D, Godsland IF, Walton C, Wynn V, .... (1992). Inverse relationship between serum Lp(a) levels and first-phase insulin secretion. Diabetes, 41(10)
- Gergely S, Walton C & Economides AP. (1992). Measurement of unipolar paced-evoked potentials. IEE Proceedings A: Physical Science. Measurement and Instrumentation. Management and Education. Reviews, 1(n)
- Baig MW, Walton C, Economides AP & Perrins EJ. (1992). A comparison of two techniques for the elimination of post-stimulus polarisation potentials. European Journal of Cardiac Pacing and Electrophysiology, 2(1)
- Wynn V, Godsland I, Walton C, Astrup A, Walker ARP, .... (1990). Can lifestyle changes reverse coronary heart disease?. The Lancet, 336(8715)
- WALTON C, ECONOMIDES AP & GERGELY S. (1989). Determination of Myocardial Depolarization and Repolarization Times Using the Unipolar Ventricular Evoked Potential: Contrasting Effects of Stimulus Interval and Isoprenaline in the Isolated Perfused Rahhit Heart. Pacing and Clinical Electrophysiology, 12(5)
- MANLEY BS, CHONG EM, WALTON C, ECONOMIDES AP & COBBE SM. (1989). An animal model for the chronic study of ventricular repolarisation and refractory period. Cardiovascular Research, 23(1)
- Gergely S, Walton C & Economides AP. (1989). Measurement of unipolar paced-evoked potentials. IEE Proceedings A (Physical Science, Measurement and Instrumentation, Management and Education), 136(4)
- WALTON C & ECONOMIDES AP. (1988). In Vitro Estimation of the Electrical Performance of Bipolar Pacing Electrode Systems. Pacing and Clinical Electrophysiology, 11(11)
- ECONOMIDES AP, WALTON C & GERGELY S. (1988). The Ventricular Intracardiac Unipolar Paced‐Evoked Potential in an Isolated Animal Heart. Pacing and Clinical Electrophysiology, 11(2)
- WALTON C, GERGELY S & ECONOMIDES AP. (1987). Platinum Pacemaker Electrodes: Origins and Effects of the Electrode‐Tissue Interface Impedance. Pacing and Clinical Electrophysiology, 10(1)
Conference Papers
- Francis D, Hodgkinson J, Walton C, Sizer J, Black P, .... (2017). Mid-IR spectroscopic instrumentation for point-of-care diagnosis using a hollow silica waveguide gas cell
- Hutter V, Murnane D, Reitdorf K, Fowler D, Walton C, .... (2015). IN VITRO ASSESSMENT OF ALVEOLAR MACROPHAGE RESPONSES TO INHALED PARTICULATE MEDICINES
- Jia W, Griffiths L, Whitehead R, Basser SJ, Dawson C, .... (2010). PWE-033 Abundance of sulphate reducing bacteria in inflammatory bowel disease
- Orsi R, Turner C, Walton C, Pollard SJT, Daly P, .... (2008). Evaluation of vapour emissions aiming former gasholder decommissioning
- Walton C, Turner C, Hoashi S, Tan CY, Swamy A, .... (2008). Detection of exhaled volatile organic compounds in breath may offer a non-invasive alternative to capillary blood glucose testing
- Turner C, Walton C, Hoashi S, Tan CY, Swamy A, .... (2008). Metabolic monitoring of volatile organic compounds excreted through skin: A novel alternative to capillary blood glucose monitoring?
- GODSLAND IF, WALTON C & STEVENSON JC. (1994). CARBOHYDRATE METABOLISM, CARDIOVASCULAR DISEASE AND HORMONE REPLACEMENT THERAPY
- SWAN JW, WALTON C, LEES B, GODSLAND IF, CROOK D, .... (1994). INSULIN-RESISTANCE SYNDROME IN PATIENTS WITH ANGINA
- SWAN JW, WALTON C, GODSLAND IF, COATS AJS & OLIVER MF. (1994). INSULIN-RESISTANCE IN CHRONIC HEART-FAILURE
- SWAN JW, WALTON C, GODSLAND IF, CLARK AL, COATS AJS, .... (1994). RELATIONSHIP OF INSULIN-RESISTANCE TO THE SEVERITY AND ETIOLOGY OF CHRONIC HEART-FAILURE
- Stevenson JC, Proudler AJ, Walton C & Godsland IF. (1994). HRT mechanisms of action: Carbohydrates
- Godsland IF, Walton C, Crook D & Wynn V. (1992). Insulin resistance ? modelling studies
