Nanotoxicology

The in vitro nanotoxicology group led by Dr Zhu has a strong focus on developing in vitro methods for toxicological evaluation of nanomaterials. Working together with other teams across Cranfield University and wider European and international partners, the group has established a strong capacity in integration of nanomaterial development, characterization, and toxicological evaluation. The group’s research has important implications for both safe development of nanotechnology and application of alternative approaches to animals for toxicity test of a broad range of nanomaterials. In order to benefit a wider society outside Cranfield University, Dr Zhu’s group also aims to transfer the outcomes of Cranfield research into nanotechnology focused services, offering opportunities for sharing resources, tools and knowledge, and therefore to support innovation of nanotechnology.

The group provides a range of expertise and services including:

Nanoparticle characterization: SEM and TEM imaging of nanoparticle size and mophorlogy, Zeta potential, hydrodynamic diameter and dispersion pattern analysis using Malvern instruments, and FT-IR analysis of nanoparticle chemistry.
In vitro toxicity testing: cytotoxicity endpoint assays using a range of cell lines of human tissue origins.
Assessment of the possible release of airborne nanoparticles from nanoproducts: simulating different conditions in testing chamber and monitoring the release of airborne nanoparticles from testing samples.
The group is also interested in joining consortia for collaborative research involving in vitro biological and toxicological evaluation of nanomaterials/nanoparticles.